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Seven Ambiguities in Explaining the Human Memory System in the Principles of Neural Science Book.
Batouli SAH. Batouli SAH. Basic Clin Neurosci. 2023 Jul-Aug;14(4):543-548. doi: 10.32598/bcn.2023.1774.4. Epub 2023 Jul 1. Basic Clin Neurosci. 2023. PMID: 38050574 Free PMC article.
Here, I share those points, either to find an answer to them or to let them be a suggestion for our future works. Professor Kandel has spent most of his meritorious lifetime studying the memory system; however, the brain is extremely complex, and as a result, we still have …
Here, I share those points, either to find an answer to them or to let them be a suggestion for our future works. Professor Kandel ha …
Cell Cycle Stage Classification Using Phase Imaging with Computational Specificity.
He YR, He S, Kandel ME, Lee YJ, Hu C, Sobh N, Anastasio MA, Popescu G. He YR, et al. ACS Photonics. 2022 Apr 20;9(4):1264-1273. doi: 10.1021/acsphotonics.1c01779. Epub 2022 Mar 8. ACS Photonics. 2022. PMID: 35480491 Free PMC article.
Here, we present a cell cycle detection workflow using the principle of phase imaging with computational specificity (PICS). The proposed method uses neural networks to extract cell cycle-dependent features from quantitative phase imaging (QPI) measurements directly …
Here, we present a cell cycle detection workflow using the principle of phase imaging with computational specificity (PICS). The prop …
Computational interference microscopy enabled by deep learning.
Jiao Y, He YR, Kandel ME, Liu X, Lu W, Popescu G. Jiao Y, et al. APL Photonics. 2021 Apr;6(4):046103. doi: 10.1063/5.0041901. Epub 2021 Apr 6. APL Photonics. 2021. PMID: 35308602 Free PMC article.
The average peak signal-to-noise ratio, Pearson correlation coefficient, and structural similarity index measure were 29.97, 0.79, and 0.82 for the test dataset. Furthermore, we implemented the neural network inference into the live acquisition software, which now allows a …
The average peak signal-to-noise ratio, Pearson correlation coefficient, and structural similarity index measure were 29.97, 0.79, and 0.82 …
Wolf phase tomography (WPT) of transparent structures using partially coherent illumination.
Chen X, Kandel ME, Hu C, Lee YJ, Popescu G. Chen X, et al. Light Sci Appl. 2020 Aug 19;9:142. doi: 10.1038/s41377-020-00379-4. eCollection 2020. Light Sci Appl. 2020. PMID: 32864117 Free PMC article.
WPT reconstruction works directly in the space-time domain, without the need for Fourier transformation, and decouples the refractive index (RI) distribution from the thickness of the sample. We demonstrate the WPT principle using the data acquired by a quantitative-phase- …
WPT reconstruction works directly in the space-time domain, without the need for Fourier transformation, and decouples the refractive index …
Event-driven simulation of cerebellar granule cells.
Carrillo RR, Ros E, Tolu S, Nieus T, D'Angelo E. Carrillo RR, et al. Biosystems. 2008 Oct-Nov;94(1-2):10-7. doi: 10.1016/j.biosystems.2008.05.007. Epub 2008 Jun 20. Biosystems. 2008. PMID: 18616981
Around half of the neurons of a human brain are granule cells (approximately 10(11)granule neurons) [Kandel, E.R., Schwartz, J.H., Jessell, T.M., 2000. Principles of Neural Science. ...Neural Computation 18 (12), 2959-2993]. For this purpose it …
Around half of the neurons of a human brain are granule cells (approximately 10(11)granule neurons) [Kandel, E.R., Schwartz, J.H., Je …
Eric Kandel: the future of memory.
Kandel E. Kandel E. Mol Interv. 2005 Apr;5(2):65-9. doi: 10.1124/mi.5.2.2. Mol Interv. 2005. PMID: 15821153
Watching ice floes glide by on the Hudson River from Eric Kandel's office, one gets a sense of placid reflection tempered by constant action-an apt analogy for Kandel's ability to calmly manage several ongoing projects and commitments at once. ...In ad …
Watching ice floes glide by on the Hudson River from Eric Kandel's office, one gets a sense of placid reflection tempered by c …
[Nobel prize in physiology of medicine for year 2000 for research of signal transduction in the nervous system].
Gispen WH. Gispen WH. Ned Tijdschr Geneeskd. 2000 Nov 11;144(46):2184-7. Ned Tijdschr Geneeskd. 2000. PMID: 11103253 Dutch.
Phosphorylation by the cyclic-AMP-dependent kinase influences its protein phosphatase inhibiting capacity and, as such, DARPP-32 is an important 'feed-forward activator' in the dopamine signal transduction cascade. Kandel received the prize for his contributions to our und …
Phosphorylation by the cyclic-AMP-dependent kinase influences its protein phosphatase inhibiting capacity and, as such, DARPP-32 is an impor …
An axon pacemaker: diversity in the mechanism of generation and conduction of action potentials in snail neurons.
Maratou E, Theophilidis G. Maratou E, et al. Neuroscience. 2000;96(1):1-2. doi: 10.1016/s0306-4522(99)00529-1. Neuroscience. 2000. PMID: 10683403
One of the main principles in neuroscience is that in vertebrate motoneurons and certain interneurons the decision to initiate an action potential is made at the initial segment of the axon, the axon hillock [Kandel E. R. and Schwartz J. H. (1991) In Principles
One of the main principles in neuroscience is that in vertebrate motoneurons and certain interneurons the decision to initiate an act …