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Candidate topical microbicides bind herpes simplex virus glycoprotein B and prevent viral entry and cell-to-cell spread.
Cheshenko N, Keller MJ, MasCasullo V, Jarvis GA, Cheng H, John M, Li JH, Hogarty K, Anderson RA, Waller DP, Zaneveld LJ, Profy AT, Klotman ME, Herold BC. Cheshenko N, et al. Among authors: profy at. Antimicrob Agents Chemother. 2004 Jun;48(6):2025-36. doi: 10.1128/AAC.48.6.2025-2036.2004. Antimicrob Agents Chemother. 2004. PMID: 15155195 Free PMC article.
Candidate sulfonated and sulfated topical microbicides: comparison of anti-human immunodeficiency virus activities and mechanisms of action.
Scordi-Bello IA, Mosoian A, He C, Chen Y, Cheng Y, Jarvis GA, Keller MJ, Hogarty K, Waller DP, Profy AT, Herold BC, Klotman ME. Scordi-Bello IA, et al. Among authors: profy at. Antimicrob Agents Chemother. 2005 Sep;49(9):3607-15. doi: 10.1128/AAC.49.9.3607-3615.2005. Antimicrob Agents Chemother. 2005. PMID: 16127029 Free PMC article.
Safety and effectiveness of BufferGel and 0.5% PRO2000 gel for the prevention of HIV infection in women.
Abdool Karim SS, Richardson BA, Ramjee G, Hoffman IF, Chirenje ZM, Taha T, Kapina M, Maslankowski L, Coletti A, Profy A, Moench TR, Piwowar-Manning E, Mâsse B, Hillier SL, Soto-Torres L; HIV Prevention Trials Network (HPTN) 035 Study Team. Abdool Karim SS, et al. AIDS. 2011 Apr 24;25(7):957-66. doi: 10.1097/QAD.0b013e32834541d9. AIDS. 2011. PMID: 21330907 Free PMC article. Clinical Trial.
58 results