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Influenza A Virus Uses PSMA2 for Downregulation of the NRF2-Mediated Oxidative Stress Response.
Rashid MU, Gao A, Coombs KM. Rashid MU, et al. J Virol. 2022 Mar 9;96(5):e0199021. doi: 10.1128/jvi.01990-21. Epub 2022 Jan 12. J Virol. 2022. PMID: 35019712 Free PMC article.
However, IAV infection caused significantly higher NFR2 nuclear translocation that was inhibited in PSMA2 KD cells. This indicates that PSMA2 is required for NRF2-mediated ROS neutralization and that IAV uses PSMA2 to escape viral clearance via the NRF2-media …
However, IAV infection caused significantly higher NFR2 nuclear translocation that was inhibited in PSMA2 KD cells. This indicates th …
PSMA2 knockdown impacts expression of proteins involved in immune and cellular stress responses in human lung cells.
Rashid MU, Lorzadeh S, Gao A, Ghavami S, Coombs KM. Rashid MU, et al. Biochim Biophys Acta Mol Basis Dis. 2023 Feb;1869(2):166617. doi: 10.1016/j.bbadis.2022.166617. Epub 2022 Dec 5. Biochim Biophys Acta Mol Basis Dis. 2023. PMID: 36481484 Free article.
PSMA2 expression dysregulation has been detected in different human diseases and viral infections. No study yet has reported PSMA2 knockdown (KD) effects on the cellular proteome. METHODS: We used SOMAScan, an aptamer-based multiplexed technique, to measure >1300 …
PSMA2 expression dysregulation has been detected in different human diseases and viral infections. No study yet has reported PSMA2 …
PSMA2 promotes glioma proliferation and migration via EMT.
Zhang Y, Xiang Z, Chen L, Deng X, Liu H, Peng X. Zhang Y, et al. Pathol Res Pract. 2024 Apr;256:155278. doi: 10.1016/j.prp.2024.155278. Epub 2024 Mar 29. Pathol Res Pract. 2024. PMID: 38574629 Free article.
This study aims to elucidate the role of PSMA2 in glioma progression and its potential association with EMT. METHODS: Online tools were employed to analyze the expression patterns and survival curves of PSMA2 in gliomas. The relationship between PSMA2 and var …
This study aims to elucidate the role of PSMA2 in glioma progression and its potential association with EMT. METHODS: Online tools we …
Increased co-expression of PSMA2 and GLP-1 receptor in cervical cancer models in type 2 diabetes attenuated by Exendin-4: A translational case-control study.
Mao D, Cao H, Shi M, Wang CC, Kwong J, Li JJX, Hou Y, Ming X, Lee HM, Tian XY, Wong CK, Chow E, Kong APS, Lui VWY, Chan PKS, Chan JCN. Mao D, et al. EBioMedicine. 2021 Mar;65:103242. doi: 10.1016/j.ebiom.2021.103242. Epub 2021 Mar 6. EBioMedicine. 2021. PMID: 33684886 Free PMC article.
FINDINGS: PSMA2 expression was increased in 12 cancer types in TCGA database and cervical cancer specimens from patients with T2D (T2D vs non-T2D: 3.22 (95% confidence interval CI: 1.38, 5.05) vs 1.00 (0.66, 1.34) fold change, P = 0.01). psma2-shRNA decreased cell p …
FINDINGS: PSMA2 expression was increased in 12 cancer types in TCGA database and cervical cancer specimens from patients with T2D (T2 …
Comprehensively Analyzed Macrophage-Regulated Genes Indicate That PSMA2 Promotes Colorectal Cancer Progression.
Qi J, Hu Z, Liu S, Li F, Wang S, Wang W, Sheng X, Feng L. Qi J, et al. Front Oncol. 2021 Jan 18;10:618902. doi: 10.3389/fonc.2020.618902. eCollection 2020. Front Oncol. 2021. PMID: 33537240 Free PMC article.
PSMA2 enhanced the proliferation, migration and invasion of CRC cells. ...Collectively, these data indicate that PSMA2 is a promising target for the therapy of CRC....
PSMA2 enhanced the proliferation, migration and invasion of CRC cells. ...Collectively, these data indicate that PSMA2 is a pr …
HLA-A, HSPA5, IGFBP5 and PSMA2 Are Restriction Factors for Zika Virus Growth in Astrocytic Cells.
Sher AA, Lao YT, Coombs KM. Sher AA, et al. Viruses. 2022 Dec 29;15(1):97. doi: 10.3390/v15010097. Viruses. 2022. PMID: 36680137 Free PMC article.
Th1 and interferon signaling pathways were among the top dysregulated canonical pathways. siRNA-mediated KD of HLA-A, IGFBP5, PSMA2 and HSPA5 increased ZIKV titers and protein synthesis, indicating they are ZIKV restriction factors. ...
Th1 and interferon signaling pathways were among the top dysregulated canonical pathways. siRNA-mediated KD of HLA-A, IGFBP5, PSMA2 a …
PAN3-PSMA2 fusion resulting from a novel t(7;13)(p14;q12) chromosome translocation in a myelodysplastic syndrome that evolved into acute myeloid leukemia.
Panagopoulos I, Gorunova L, Andersen HK, Bergrem A, Dahm A, Andersen K, Micci F, Heim S. Panagopoulos I, et al. Exp Hematol Oncol. 2018 Mar 20;7:7. doi: 10.1186/s40164-018-0099-4. eCollection 2018. Exp Hematol Oncol. 2018. PMID: 29560286 Free PMC article.
The 7;13-translocation resulted in fusion of the gene PAN3 from 13q12 with PSMA2 from 7p14 to generate an out-of-frame PAN3-PSMA2 fusion transcript whose presence was verified by RT-PCR together with Sanger sequencing. Interphase fluorescence in situ hybridization a …
The 7;13-translocation resulted in fusion of the gene PAN3 from 13q12 with PSMA2 from 7p14 to generate an out-of-frame PAN3-PSMA2 …
UCHL-3 as a potential biomarker of ovarian cancer.
Yang Q, Peng X, Nian Z, Yuan S, Wang Z, Song Y, Shamsnur R, Wang H, Yi T. Yang Q, et al. Gynecol Oncol. 2024 Mar;182:156-167. doi: 10.1016/j.ygyno.2023.12.031. Epub 2024 Jan 23. Gynecol Oncol. 2024. PMID: 38266402 Free article.
Subsequently, a UCHL3-related prognostic signature was built based on six prognostic genes (PI3, TFAP2B, MUC7, PSMA2, PIK3C2G, and NME1). Independent prognostic analysis suggested that age, tumor mutational burden, and RiskScore can be used as independent prognostic factor …
Subsequently, a UCHL3-related prognostic signature was built based on six prognostic genes (PI3, TFAP2B, MUC7, PSMA2, PIK3C2G, and NM …
Cellular stress responses of Eleginops maclovinus fish injected with Piscirickettsia salmonis and submitted to thermal stress.
Martínez D, Vargas-Lagos C, Saravia J, Oyarzún R, Loncoman C, Pontigo JP, Vargas-Chacoff L. Martínez D, et al. Cell Stress Chaperones. 2020 Jan;25(1):93-104. doi: 10.1007/s12192-019-01051-6. Epub 2019 Dec 13. Cell Stress Chaperones. 2020. PMID: 31834618 Free PMC article.
The genes implied in the heat shock response (HSP70, HSC70, HSP90, and GRP78), apoptosis pathway (BAX and SMAC/Diablo), ubiquitination (E2, E3, ubiquitin, and CHIP), and 26 proteasome complex (PSMB7, PSMC1, and PSMA2) showed expression profiles dependent on time and type o …
The genes implied in the heat shock response (HSP70, HSC70, HSP90, and GRP78), apoptosis pathway (BAX and SMAC/Diablo), ubiquitination (E2, …
51 results