Synthesis of antiproliferative flavones from calycopterin, major flavonoid of Calycopteris floribunda Lamk.
Lewin G, Shridhar NB, Aubert G, Thoret S, Dubois J, Cresteil T.
Lewin G, et al.
Bioorg Med Chem. 2011 Jan 1;19(1):186-96. doi: 10.1016/j.bmc.2010.11.035. Epub 2010 Nov 20.
Bioorg Med Chem. 2011.
PMID: 21146994
Eighteen new analogues of 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxy-flavone, a potent natural cytotoxic and antimitotic flavone, were synthesized from calycopterin, the major flavonoid of Calycopteris floribunda Lamk., a traditional Asian medicinal plant. One of them, the 3'- …
Eighteen new analogues of 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxy-flavone, a potent natural cytotoxic and antimitotic flavone, were synthesiz …