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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 2
1995 1
1996 40
1997 110
1998 129
1999 202
2000 209
2001 251
2002 279
2003 279
2004 238
2005 166
2006 59
2007 68
2008 84
2009 88
2010 59
2011 63
2012 110
2013 114
2014 89
2015 97
2016 72
2017 75
2018 75
2019 83
2020 87
2021 67
2022 59
2023 40
2024 19

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3,069 results

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Page 1
The PTGS1 (rs1330344) CC Genotype Contributes to Susceptibility to Kawasaki Disease in Southern Chinese Children.
Zheng H, Fu L, Xu Y, Zhang TF, Che D, Li JQ, Zhou H, Jiang Z, Lin K, Zhang L, Pi L, Gu X. Zheng H, et al. Angiology. 2023 Oct;74(9):832-839. doi: 10.1177/00033197221118343. Epub 2022 Sep 2. Angiology. 2023. PMID: 36056535
Although polymorphisms in prostaglandin-endoperoxide synthase 1 (PTGS1) are being increasingly explored in cardiovascular diseases, little is known regarding the connection between PTGS1 polymorphisms and KD risk. We evaluated 834 KD patients and 1474 healthy contro …
Although polymorphisms in prostaglandin-endoperoxide synthase 1 (PTGS1) are being increasingly explored in cardiovascular diseases, l …
Mechanisms of Damage to the Gastrointestinal Tract From Nonsteroidal Anti-Inflammatory Drugs.
Bjarnason I, Scarpignato C, Holmgren E, Olszewski M, Rainsford KD, Lanas A. Bjarnason I, et al. Gastroenterology. 2018 Feb;154(3):500-514. doi: 10.1053/j.gastro.2017.10.049. Epub 2017 Dec 6. Gastroenterology. 2018. PMID: 29221664 Free article. Review.
Although mechanisms of damage involve the activities of prostaglandin-endoperoxide synthase 1 (PTGS1 or cyclooxygenase [COX] 1) and PTGS1 (COX2), other factors are involved. ...
Although mechanisms of damage involve the activities of prostaglandin-endoperoxide synthase 1 (PTGS1 or cyclooxygenase [COX] 1) and …
Androgen deprivation-induced ZBTB46-PTGS1 signaling promotes neuroendocrine differentiation of prostate cancer.
Chen WY, Zeng T, Wen YC, Yeh HL, Jiang KC, Chen WH, Zhang Q, Huang J, Liu YN. Chen WY, et al. Cancer Lett. 2019 Jan;440-441:35-46. doi: 10.1016/j.canlet.2018.10.004. Epub 2018 Oct 9. Cancer Lett. 2019. PMID: 30312731
In addition, ZBTB46 acts as a transcriptional coactivator that binds to the promoter of prostaglandin-endoperoxide synthase 1 (PTGS1) and transcriptionally regulated PTGS1 levels. Overexpression of ZBTB46 decreases the sensitivity of the combination of enzalutamide …
In addition, ZBTB46 acts as a transcriptional coactivator that binds to the promoter of prostaglandin-endoperoxide synthase 1 (PTGS1) …
Partial in vivo reprogramming enables injury-free intestinal regeneration via autonomous Ptgs1 induction.
Kim J, Kim S, Lee SY, Jo BK, Oh JY, Kwon EJ, Kim KT, Adpaikar AA, Kim EJ, Jung HS, Kim HR, Roe JS, Hong CP, Kim JK, Koo BK, Cha HJ. Kim J, et al. Sci Adv. 2023 Nov 24;9(47):eadi8454. doi: 10.1126/sciadv.adi8454. Epub 2023 Nov 24. Sci Adv. 2023. PMID: 38000027 Free PMC article.
In contrast to normal intestinal regeneration involving Ptgs2 induction, the OSKM promotes autonomous production of prostaglandin E2 via epithelial Ptgs1 expression. These results indicate prostaglandin synthesis is a common mechanism for intestinal regeneration but involv …
In contrast to normal intestinal regeneration involving Ptgs2 induction, the OSKM promotes autonomous production of prostaglandin E2 via epi …
EVI1 upregulates PTGS1 (COX1) and decreases the action of tyrosine kinase inhibitors (TKIs) in chronic myeloid leukemia cells.
Vinothkumar K, Chanda S, Singh VK, Biswas S, Mohapatra S, Biswas G, Chakraborty S. Vinothkumar K, et al. Int J Hematol. 2023 Jan;117(1):110-120. doi: 10.1007/s12185-022-03465-y. Epub 2022 Oct 25. Int J Hematol. 2023. PMID: 36282419
In this study, we used RNA sequencing followed by RQ-PCR to show that the proto-oncogene EVI1 targets the drug-metabolizing gene PTGS1 in CML. The PTGS1 promoter element had an EVI1 binding site, and CHIP assay confirmed its presence. ...Furthermore, combined inhibi …
In this study, we used RNA sequencing followed by RQ-PCR to show that the proto-oncogene EVI1 targets the drug-metabolizing gene PTGS1 …
MYLK and PTGS1 Genetic Variations Associated with Osteoporosis and Benign Breast Tumors in Korean Women.
Cho HW, Jin HS, Eom YB. Cho HW, et al. Genes (Basel). 2021 Mar 6;12(3):378. doi: 10.3390/genes12030378. Genes (Basel). 2021. PMID: 33800915 Free PMC article.
There were 60 single nucleotide polymorphisms (SNPs) and 12 SNPs in the MYLK and PTGS1 genes, associated with benign breast tumors and osteoporosis. ...Our results suggest that both the MYLK and PTGS1 genes are genetic factors associated with the phenotypes, and the …
There were 60 single nucleotide polymorphisms (SNPs) and 12 SNPs in the MYLK and PTGS1 genes, associated with benign breast tumors an …
Inhibition of PTGS1 promotes osteogenic differentiation of adipose-derived stem cells by suppressing NF-kB signaling.
Wang Y, Liu Y, Zhang M, Lv L, Zhang X, Zhang P, Zhou Y. Wang Y, et al. Stem Cell Res Ther. 2019 Feb 13;10(1):57. doi: 10.1186/s13287-019-1167-3. Stem Cell Res Ther. 2019. PMID: 30760327 Free PMC article.
Western blot and confocal analyses were used to determine the molecular mechanism of PTGS1-regulated osteogenic differentiation. RESULTS: Our work demonstrates that PTGS1 expression is significantly increased upon inflammatory cytokine treatment. Both ex vivo and in …
Western blot and confocal analyses were used to determine the molecular mechanism of PTGS1-regulated osteogenic differentiation. RESU …
Pharmacogenomics of cyclooxygenases.
Agúndez JA, Blanca M, Cornejo-García JA, García-Martín E. Agúndez JA, et al. Pharmacogenomics. 2015;16(5):501-22. doi: 10.2217/pgs.15.6. Pharmacogenomics. 2015. PMID: 25916522 Review.
Many adverse drugs reactions to NSAIDs are attributable to COX-inhibition. The genes coding for these enzymes (PTGS1 and PTGS2) are highly variable, and variations in these genes may underlie the risk of developing, or the clinical evolution of, several diseases and advers …
Many adverse drugs reactions to NSAIDs are attributable to COX-inhibition. The genes coding for these enzymes (PTGS1 and PTGS2) are h …
Association between PTGS1 polymorphisms and functional outcomes in Chinese patients with stroke during aspirin therapy: Interaction with smoking.
Cai H, Cai B, Sun L, Zhang H, Zhou S, Cao L, Guo H, Sun W, Yan B, Davis SM, Zhang Z, Liu X. Cai H, et al. J Neurol Sci. 2017 May 15;376:211-215. doi: 10.1016/j.jns.2017.03.014. Epub 2017 Mar 14. J Neurol Sci. 2017. PMID: 28431615
The influence of PTGS1 gene-smoking interaction on functional outcomes was examined. ...PTGS1 gene-smoking interaction might in part reflect the heterogeneity in the prognosis of patients treated with aspirin....
The influence of PTGS1 gene-smoking interaction on functional outcomes was examined. ...PTGS1 gene-smoking interaction might i …
3,069 results