Pu SY - Search Results

1

Feasibility and biological rationale of repurposing sunitinib and erlotinib for dengue treatment.

Pu SY, Xiao F, Schor S, Bekerman E, Zanini F, Barouch-Bentov R, Nagamine CM, Einav S. Pu SY, et al. Antiviral Res. 2018 Jul;155:67-75. doi: 10.1016/j.antiviral.2018.05.001. Epub 2018 May 16. Antiviral Res. 2018. PMID: 29753658 Free PMC article.

2

BIKE regulates dengue virus infection and is a cellular target for broad-spectrum antivirals.

Pu S, Schor S, Karim M, Saul S, Robinson M, Kumar S, Prugar LI, Dorosky DE, Brannan J, Dye JM, Einav S. Pu S, et al. Antiviral Res. 2020 Dec;184:104966. doi: 10.1016/j.antiviral.2020.104966. Epub 2020 Nov 1. Antiviral Res. 2020. PMID: 33137362 Free PMC article.

3

Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects.

Bekerman E, Neveu G, Shulla A, Brannan J, Pu SY, Wang S, Xiao F, Barouch-Bentov R, Bakken RR, Mateo R, Govero J, Nagamine CM, Diamond MS, De Jonghe S, Herdewijn P, Dye JM, Randall G, Einav S. Bekerman E, et al. Among authors: pu sy. J Clin Invest. 2017 Apr 3;127(4):1338-1352. doi: 10.1172/JCI89857. Epub 2017 Feb 27. J Clin Invest. 2017. PMID: 28240606 Free PMC article.

4

Single-cell transcriptional dynamics of flavivirus infection.

Zanini F, Pu SY, Bekerman E, Einav S, Quake SR. Zanini F, et al. Among authors: pu sy. Elife. 2018 Feb 16;7:e32942. doi: 10.7554/eLife.32942. Elife. 2018. PMID: 29451494 Free PMC article.

5

Optimization of Isothiazolo[4,3- b]pyridine-Based Inhibitors of Cyclin G Associated Kinase (GAK) with Broad-Spectrum Antiviral Activity.

Pu SY, Wouters R, Schor S, Rozenski J, Barouch-Bentov R, Prugar LI, O'Brien CM, Brannan JM, Dye JM, Herdewijn P, De Jonghe S, Einav S. Pu SY, et al. J Med Chem. 2018 Jul 26;61(14):6178-6192. doi: 10.1021/acs.jmedchem.8b00613. Epub 2018 Jul 16. J Med Chem. 2018. PMID: 29953812 Free PMC article.

6

Cyclin G-associated kinase (GAK) affinity and antiviral activity studies of a series of 3-C-substituted isothiazolo[4,3-b]pyridines.

Wouters R, Pu SY, Froeyen M, Lescrinier E, Einav S, Herdewijn P, De Jonghe S. Wouters R, et al. Among authors: pu sy. Eur J Med Chem. 2019 Feb 1;163:256-265. doi: 10.1016/j.ejmech.2018.11.065. Epub 2018 Nov 28. Eur J Med Chem. 2019. PMID: 30529544

7

Synthesis and Structure-Activity Relationships of 3,5-Disubstituted-pyrrolo[2,3- b]pyridines as Inhibitors of Adaptor-Associated Kinase 1 with Antiviral Activity.

Verdonck S, Pu SY, Sorrell FJ, Elkins JM, Froeyen M, Gao LJ, Prugar LI, Dorosky DE, Brannan JM, Barouch-Bentov R, Knapp S, Dye JM, Herdewijn P, Einav S, De Jonghe S. Verdonck S, et al. Among authors: pu sy. J Med Chem. 2019 Jun 27;62(12):5810-5831. doi: 10.1021/acs.jmedchem.9b00136. Epub 2019 Jun 12. J Med Chem. 2019. PMID: 31136173 Free PMC article.

8

Structure-activity relationship study of the pyridine moiety of isothiazolo[4,3-b]pyridines as antiviral agents targeting cyclin G-associated kinase.

Martinez-Gualda B, Pu SY, Froeyen M, Herdewijn P, Einav S, De Jonghe S. Martinez-Gualda B, et al. Among authors: pu sy. Bioorg Med Chem. 2020 Jan 1;28(1):115188. doi: 10.1016/j.bmc.2019.115188. Epub 2019 Nov 11. Bioorg Med Chem. 2020. PMID: 31757682

9

Interactions between the Hepatitis C Virus Nonstructural 2 Protein and Host Adaptor Proteins 1 and 4 Orchestrate Virus Release.

Xiao F, Wang S, Barouch-Bentov R, Neveu G, Pu S, Beer M, Schor S, Kumar S, Nicolaescu V, Lindenbach BD, Randall G, Einav S. Xiao F, et al. mBio. 2018 Mar 13;9(2):e02233-17. doi: 10.1128/mBio.02233-17. mBio. 2018. PMID: 29535204 Free PMC article.

10

MARCH8 Ubiquitinates the Hepatitis C Virus Nonstructural 2 Protein and Mediates Viral Envelopment.

Kumar S, Barouch-Bentov R, Xiao F, Schor S, Pu S, Biquand E, Lu A, Lindenbach BD, Jacob Y, Demeret C, Einav S. Kumar S, et al. Cell Rep. 2019 Feb 12;26(7):1800-1814.e5. doi: 10.1016/j.celrep.2019.01.075. Cell Rep. 2019. PMID: 30759391 Free PMC article.

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