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Novel mitochondria-targeted antioxidants: plastoquinone conjugated with cationic plant alkaloids berberine and palmatine.
Lyamzaev KG, Pustovidko AV, Simonyan RA, Rokitskaya TI, Domnina LV, Ivanova OY, Severina II, Sumbatyan NV, Korshunova GA, Tashlitsky VN, Roginsky VA, Antonenko YN, Skulachev MV, Chernyak BV, Skulachev VP. Lyamzaev KG, et al. Among authors: pustovidko av. Pharm Res. 2011 Nov;28(11):2883-95. doi: 10.1007/s11095-011-0504-8. Epub 2011 Jun 14. Pharm Res. 2011. PMID: 21671134
Derivatives of rhodamine 19 as mild mitochondria-targeted cationic uncouplers.
Antonenko YN, Avetisyan AV, Cherepanov DA, Knorre DA, Korshunova GA, Markova OV, Ojovan SM, Perevoshchikova IV, Pustovidko AV, Rokitskaya TI, Severina II, Simonyan RA, Smirnova EA, Sobko AA, Sumbatyan NV, Severin FF, Skulachev VP. Antonenko YN, et al. Among authors: pustovidko av. J Biol Chem. 2011 May 20;286(20):17831-40. doi: 10.1074/jbc.M110.212837. Epub 2011 Mar 30. J Biol Chem. 2011. PMID: 21454507 Free PMC article.
Novel penetrating cations for targeting mitochondria.
Chernyak BV, Antonenko YN, Domnina LV, Ivanova OY, Lyamzaev KG, Pustovidko AV, Rokitskaya TI, Severina II, Simonyan RA, Trendeleva TA, Zvyagilskaya RA. Chernyak BV, et al. Among authors: pustovidko av. Curr Pharm Des. 2013;19(15):2795-806. doi: 10.2174/1381612811319150015. Curr Pharm Des. 2013. PMID: 23092317 Review.
Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 1. Cationic plastoquinone derivatives: synthesis and in vitro studies.
Antonenko YN, Avetisyan AV, Bakeeva LE, Chernyak BV, Chertkov VA, Domnina LV, Ivanova OY, Izyumov DS, Khailova LS, Klishin SS, Korshunova GA, Lyamzaev KG, Muntyan MS, Nepryakhina OK, Pashkovskaya AA, Pletjushkina OY, Pustovidko AV, Roginsky VA, Rokitskaya TI, Ruuge EK, Saprunova VB, Severina II, Simonyan RA, Skulachev IV, Skulachev MV, Sumbatyan NV, Sviryaeva IV, Tashlitsky VN, Vassiliev JM, Vyssokikh MY, Yaguzhinsky LS, Zamyatnin AA Jr, Skulachev VP. Antonenko YN, et al. Among authors: pustovidko av. Biochemistry (Mosc). 2008 Dec;73(12):1273-87. doi: 10.1134/s0006297908120018. Biochemistry (Mosc). 2008. PMID: 19120014 Free article.
Novel mitochondria-targeted compounds composed of natural constituents: conjugates of plant alkaloids berberine and palmatine with plastoquinone.
Chernyak BV, Antonenko YN, Galimov ER, Domnina LV, Dugina VB, Zvyagilskaya RA, Ivanova OY, Izyumov DS, Lyamzaev KG, Pustovidko AV, Rokitskaya TI, Rogov AG, Severina II, Simonyan RA, Skulachev MV, Tashlitsky VN, Titova EV, Trendeleva TA, Shagieva GS. Chernyak BV, et al. Among authors: pustovidko av. Biochemistry (Mosc). 2012 Sep;77(9):983-95. doi: 10.1134/S0006297912090040. Biochemistry (Mosc). 2012. PMID: 23157257 Free article. Review.
Penetrating cation/fatty acid anion pair as a mitochondria-targeted protonophore.
Severin FF, Severina II, Antonenko YN, Rokitskaya TI, Cherepanov DA, Mokhova EN, Vyssokikh MY, Pustovidko AV, Markova OV, Yaguzhinsky LS, Korshunova GA, Sumbatyan NV, Skulachev MV, Skulachev VP. Severin FF, et al. Among authors: pustovidko av. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):663-8. doi: 10.1073/pnas.0910216107. Epub 2009 Dec 18. Proc Natl Acad Sci U S A. 2010. PMID: 20080732 Free PMC article.
Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1.
Shabalina IG, Vyssokikh MY, Gibanova N, Csikasz RI, Edgar D, Hallden-Waldemarson A, Rozhdestvenskaya Z, Bakeeva LE, Vays VB, Pustovidko AV, Skulachev MV, Cannon B, Skulachev VP, Nedergaard J. Shabalina IG, et al. Among authors: pustovidko av. Aging (Albany NY). 2017 Feb 15;9(2):315-339. doi: 10.18632/aging.101174. Aging (Albany NY). 2017. PMID: 28209927 Free PMC article.
19 results