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STAT5 Is a Key Regulator in NK Cells and Acts as a Molecular Switch from Tumor Surveillance to Tumor Promotion.
Gotthardt D, Putz EM, Grundschober E, Prchal-Murphy M, Straka E, Kudweis P, Heller G, Bago-Horvath Z, Witalisz-Siepracka A, Cumaraswamy AA, Gunning PT, Strobl B, Müller M, Moriggl R, Stockmann C, Sexl V. Gotthardt D, et al. Among authors: putz em. Cancer Discov. 2016 Apr;6(4):414-29. doi: 10.1158/2159-8290.CD-15-0732. Epub 2016 Feb 12. Cancer Discov. 2016. PMID: 26873347
Leukemic challenge unmasks a requirement for PI3Kdelta in NK cell-mediated tumor surveillance.
Zebedin E, Simma O, Schuster C, Putz EM, Fajmann S, Warsch W, Eckelhart E, Stoiber D, Weisz E, Schmid JA, Pickl WF, Baumgartner C, Valent P, Piekorz RP, Freissmuth M, Sexl V. Zebedin E, et al. Among authors: putz em. Blood. 2008 Dec 1;112(12):4655-64. doi: 10.1182/blood-2008-02-139105. Epub 2008 Aug 6. Blood. 2008. PMID: 18684865 Free article.
The cooperating mutation or "second hit" determines the immunologic visibility toward MYC-induced murine lymphomas.
Schuster C, Berger A, Hoelzl MA, Putz EM, Frenzel A, Simma O, Moritz N, Hoelbl A, Kovacic B, Freissmuth M, Müller M, Villunger A, Müllauer L, Schmatz AI, Streubel B, Porpaczy E, Jäger U, Stoiber D, Sexl V. Schuster C, et al. Among authors: putz em. Blood. 2011 Oct 27;118(17):4635-45. doi: 10.1182/blood-2010-10-313098. Epub 2011 Aug 30. Blood. 2011. PMID: 21878673 Free article.
PI3Kδ is essential for tumor clearance mediated by cytotoxic T lymphocytes.
Putz EM, Prchal-Murphy M, Simma OA, Forster F, Koenig X, Stockinger H, Piekorz RP, Freissmuth M, Müller M, Sexl V, Zebedin-Brandl E. Putz EM, et al. PLoS One. 2012;7(7):e40852. doi: 10.1371/journal.pone.0040852. Epub 2012 Jul 13. PLoS One. 2012. PMID: 22808277 Free PMC article.
Bcl-2: Live and let die.
Putz EM, Schuster C, Sexl V. Putz EM, et al. Oncoimmunology. 2012 Aug 1;1(5):749-750. doi: 10.4161/onci.19536. Oncoimmunology. 2012. PMID: 22934270 Free PMC article.
Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance.
Mizutani T, Neugebauer N, Putz EM, Moritz N, Simma O, Zebedin-Brandl E, Gotthardt D, Warsch W, Eckelhart E, Kantner HP, Kalinke U, Lienenklaus S, Weiss S, Strobl B, Müller M, Sexl V, Stoiber D. Mizutani T, et al. Among authors: putz em. Oncoimmunology. 2012 Oct 1;1(7):1027-1037. doi: 10.4161/onci.21284. Oncoimmunology. 2012. PMID: 23170251 Free PMC article.
Targeting PI3Kδ: One man's meat is another man's poison.
Prchal-Murphy M, Putz EM, Freissmuth M, Sexl V, Zebedin-Brandl E. Prchal-Murphy M, et al. Among authors: putz em. Oncoimmunology. 2013 Jan 1;2(1):e22272. doi: 10.4161/onci.22272. Oncoimmunology. 2013. PMID: 23482629 Free PMC article.
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