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The APC/C activator FZR1 is essential for meiotic prophase I in mice.
Holt JE, Pye V, Boon E, Stewart JL, García-Higuera I, Moreno S, Rodríguez R, Jones KT, McLaughlin EA. Holt JE, et al. Among authors: pye v. Development. 2014 Mar;141(6):1354-65. doi: 10.1242/dev.104828. Epub 2014 Feb 19. Development. 2014. PMID: 24553289 Free article.
Dynamin 2 is essential for mammalian spermatogenesis.
Redgrove KA, Bernstein IR, Pye VJ, Mihalas BP, Sutherland JM, Nixon B, McCluskey A, Robinson PJ, Holt JE, McLaughlin EA. Redgrove KA, et al. Sci Rep. 2016 Oct 11;6:35084. doi: 10.1038/srep35084. Sci Rep. 2016. PMID: 27725702 Free PMC article.
Quinolone-1-(2H)-ones as hedgehog signalling pathway inhibitors.
Trinh TN, McLaughlin EA, Abdel-Hamid MK, Gordon CP, Bernstein IR, Pye V, Cossar P, Sakoff JA, McCluskey A. Trinh TN, et al. Among authors: pye v. Org Biomol Chem. 2016 Jul 14;14(26):6304-15. doi: 10.1039/c6ob00606j. Epub 2016 Jun 7. Org Biomol Chem. 2016. PMID: 27272335
Small molecule Hedgehog pathway antagonists.
Trinh TN, McLaughlin EA, Gordon CP, Bernstein IR, Pye VJ, Redgrove KA, McCluskey A. Trinh TN, et al. Org Biomol Chem. 2017 Apr 5;15(14):3046-3059. doi: 10.1039/c6ob01959e. Org Biomol Chem. 2017. PMID: 28318003
71 results