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pyrf
(170 results)?
Defining mitochondrial protein functions through deep multiomic profiling.
Nature. 2022 Jun;606(7913):382-388. doi: 10.1038/s41586-022-04765-3. Epub 2022 May 25.
Nature. 2022.
PMID: 35614220
Free PMC article.
Guided by these data, we discovered that PIGY upstream open reading frame (PYURF) is an S-adenosylmethionine-dependent methyltransferase chaperone that supports both complex I assembly and coenzyme Q biosynthesis and is disrupted in a previously unresolved multisystemic mi …
Guided by these data, we discovered that PIGY upstream open reading frame (PYURF) is an S-adenosylmethionine-dependent methyltransfer …
Human mitochondrial protein complexes revealed by large-scale coevolution analysis and deep learning-based structure modeling.
Pei J, Zhang J, Cong Q.
Pei J, et al.
Bioinformatics. 2022 Sep 15;38(18):4301-4311. doi: 10.1093/bioinformatics/btac527.
Bioinformatics. 2022.
PMID: 35881696
For high-scoring pairs without experimental complex structures, our coevolution analyses and structural models shed light on the details of their interfaces, including CHCHD4-AIFM1, MTERF3-TRUB2, FMC1-ATPAF2 and ECSIT-NDUFAF1. We also identified novel PPIs (PYURF-NDUFAF5, …
For high-scoring pairs without experimental complex structures, our coevolution analyses and structural models shed light on the details of …
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Unraveling inbreeding patterns and selection signals in Alpine Grey cattle.
Gomez Proto G, Mancin E, Sartori C, Mantovani R.
Gomez Proto G, et al.
Animal. 2024 May;18(5):101159. doi: 10.1016/j.animal.2024.101159. Epub 2024 Apr 16.
Animal. 2024.
PMID: 38718700
Free article.
Two major ROH islands on chromosomes 6 and 7 harbored genes linked to immune response, disease resistance (PYURF, HERC3), and fertility (EIF4EBP3, SRA1). This study underscores the need for detailed inbreeding analyses to understand genetic characteristics and historical c …
Two major ROH islands on chromosomes 6 and 7 harbored genes linked to immune response, disease resistance (PYURF, HERC3), and fertili …
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Signatures of selection reveal candidate genes involved in economic traits and cold acclimation in five Swedish cattle breeds.
Ghoreishifar SM, Eriksson S, Johansson AM, Khansefid M, Moghaddaszadeh-Ahrabi S, Parna N, Davoudi P, Javanmard A.
Ghoreishifar SM, et al.
Genet Sel Evol. 2020 Sep 4;52(1):52. doi: 10.1186/s12711-020-00571-5.
Genet Sel Evol. 2020.
PMID: 32887549
Free PMC article.
Annotation of genes in these regions revealed various verified and novel candidate genes that are associated with a diverse range of traits, including e.g. high altitude adaptation and response to hypoxia (DCAF8, PPP1R12A, SLC16A3, UCP2, UCP3, TIGAR), cold acclimation (AQP3, AQP7 …
Annotation of genes in these regions revealed various verified and novel candidate genes that are associated with a diverse range of traits, …
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