Qin HL - Search Results

1

Novel Pyridine-Containing Sultones: Structure-Activity Relationship and Biological Evaluation as Selective AChE Inhibitors for the Treatment of Alzheimer's disease.

Zhang H, Wu C, Chen X, Zhang Z, Jiang X, Qin HL, Tang W. Zhang H, et al. Among authors: qin hl. ChemMedChem. 2021 Oct 15;16(20):3189-3200. doi: 10.1002/cmdc.202100272. Epub 2021 Jun 22. ChemMedChem. 2021. PMID: 34036731

2

Biological evaluation of synthetic α,β-unsaturated carbonyl based cyclohexanone derivatives as neuroprotective novel inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation.

Zha GF, Zhang CP, Qin HL, Jantan I, Sher M, Amjad MW, Hussain MA, Hussain Z, Bukhari SN. Zha GF, et al. Among authors: qin hl. Bioorg Med Chem. 2016 May 15;24(10):2352-9. doi: 10.1016/j.bmc.2016.04.015. Epub 2016 Apr 8. Bioorg Med Chem. 2016. PMID: 27083471

3

Evaluation of multifunctional synthetic tetralone derivatives for treatment of Alzheimer's disease.

Leng J, Qin HL, Zhu K, Jantan I, Hussain MA, Sher M, Amjad MW, Naeem-Ul-Hassan M, Ahmad W, Bukhari SN. Leng J, et al. Among authors: qin hl. Chem Biol Drug Des. 2016 Dec;88(6):889-898. doi: 10.1111/cbdd.12822. Epub 2016 Aug 17. Chem Biol Drug Des. 2016. PMID: 27434226

4

Recent Developments on Phenstatins as Potent Antimitotic Agents.

Chen X, Wang SM, Kumar GB, Bare GAL, Leng J, Bukhari SNA, Qin HL. Chen X, et al. Among authors: qin hl. Curr Med Chem. 2018;25(20):2329-2352. doi: 10.2174/0929867324666171106162048. Curr Med Chem. 2018. PMID: 29110592 Review.

5

Synthesis and biological evaluation of new tetramethylpyrazine-based chalcone derivatives as potential anti-Alzheimer agents.

Wang M, Qin HL, Leng J, Ameeduzzafar, Amjad MW, Raja MAG, Hussain MA, Bukhari SNA. Wang M, et al. Among authors: qin hl. Chem Biol Drug Des. 2018 Nov;92(5):1859-1866. doi: 10.1111/cbdd.13355. Epub 2018 Jul 23. Chem Biol Drug Des. 2018. PMID: 29923315

6

A portal to a class of novel sultone-functionalized pyridines via an annulative SuFEx process employing earth abundant nickel catalysts.

Chen X , Zha GF , Fang WY , Rakesh KP , Qin HL . Chen X , et al. Among authors: qin hl. Chem Commun (Camb). 2018 Aug 9;54(65):9011-9014. doi: 10.1039/c8cc04032j. Chem Commun (Camb). 2018. PMID: 30046792

7

Synthesis and molecular docking studies of xanthone attached amino acids as potential antimicrobial and anti-inflammatory agents.

Chen X, Leng J, Rakesh KP, Darshini N, Shubhavathi T, Vivek HK, Mallesha N, Qin HL. Chen X, et al. Among authors: qin hl. Medchemcomm. 2017 Jul 26;8(8):1706-1719. doi: 10.1039/c7md00209b. eCollection 2017 Aug 1. Medchemcomm. 2017. PMID: 30108882 Free PMC article.

8

Combating a Master Manipulator: Staphylococcus aureus Immunomodulatory Molecules as Targets for Combinatorial Drug Discovery.

Rakesh KP, Marichannegowda MH, Srivastava S, Chen X, Long S, Karthik CS, Mallu P, Qin HL. Rakesh KP, et al. Among authors: qin hl. ACS Comb Sci. 2018 Dec 10;20(12):681-693. doi: 10.1021/acscombsci.8b00088. Epub 2018 Nov 8. ACS Comb Sci. 2018. PMID: 30372025 Review.

9

SO₂F₂-Mediated Oxidative Dehydrogenation and Dehydration of Alcohols to Alkynes.

Zha GF, Fang WY, Li YG, Leng J, Chen X, Qin HL. Zha GF, et al. Among authors: qin hl. J Am Chem Soc. 2018 Dec 19;140(50):17666-17673. doi: 10.1021/jacs.8b10069. Epub 2018 Dec 11. J Am Chem Soc. 2018. PMID: 30481008

10

Discovery of δ-sultone-fused pyrazoles for treating Alzheimer's disease: Design, synthesis, biological evaluation and SAR studies.

Xu Y, Zhang Z, Jiang X, Chen X, Wang Z, Alsulami H, Qin HL, Tang W. Xu Y, et al. Among authors: qin hl. Eur J Med Chem. 2019 Nov 1;181:111598. doi: 10.1016/j.ejmech.2019.111598. Epub 2019 Aug 6. Eur J Med Chem. 2019. PMID: 31415981

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