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Novel alpha-7 nicotinic acetylcholine receptor agonists containing a urea moiety: identification and characterization of the potent, selective, and orally efficacious agonist 1-[6-(4-fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl) urea (SEN34625/WYE-103914).
Ghiron C, Haydar SN, Aschmies S, Bothmann H, Castaldo C, Cocconcelli G, Comery TA, Di L, Dunlop J, Lock T, Kramer A, Kowal D, Jow F, Grauer S, Harrison B, La Rosa S, Maccari L, Marquis KL, Micco I, Nencini A, Quinn J, Robichaud AJ, Roncarati R, Scali C, Terstappen GC, Turlizzi E, Valacchi M, Varrone M, Zanaletti R, Zanelli U. Ghiron C, et al. Among authors: quinn j. J Med Chem. 2010 Jun 10;53(11):4379-89. doi: 10.1021/jm901692q. J Med Chem. 2010. PMID: 20465311
Structure-activity relationship and properties optimization of a series of quinazoline-2,4-diones as inhibitors of the canonical Wnt pathway.
Nencini A, Pratelli C, Quinn JM, Salerno M, Tunici P, De Robertis A, Valensin S, Mennillo F, Rossi M, Bakker A, Benicchi T, Cappelli F, Turlizzi E, Nibbio M, Caradonna NP, Zanelli U, Andreini M, Magnani M, Varrone M. Nencini A, et al. Eur J Med Chem. 2015 May 5;95:526-45. doi: 10.1016/j.ejmech.2015.03.055. Epub 2015 Mar 25. Eur J Med Chem. 2015. PMID: 25847770
A novel series of benzimidazole NR2B-selective NMDA receptor antagonists.
Davies DJ, Crowe M, Lucas N, Quinn J, Miller DD, Pritchard S, Grose D, Bettini E, Calcinaghi N, Virginio C, Abberley L, Goldsmith P, Michel AD, Chessell IP, Kew JN, Miller ND, Gunthorpe MJ. Davies DJ, et al. Among authors: quinn j. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2620-3. doi: 10.1016/j.bmcl.2012.01.108. Epub 2012 Feb 6. Bioorg Med Chem Lett. 2012. PMID: 22366657
Global arthropod beta-diversity is spatially and temporally structured by latitude.
Seymour M, Roslin T, deWaard JR, Perez KHJ, D'Souza ML, Ratnasingham S, Ashfaq M, Levesque-Beaudin V, Blagoev GA, Bukowski B, Cale P, Crosbie D, Decaëns T, deWaard SL, Ekrem T, El-Ansary HO, Evouna Ondo F, Fraser D, Geiger MF, Hajibabaei M, Hallwachs W, Hanisch PE, Hausmann A, Heath M, Hogg ID, Janzen DH, Kinnaird M, Kohn JR, Larrivée M, Lees DC, León-Règagnon V, Liddell M, Lijtmaer DA, Lipinskaya T, Locke SA, Manjunath R, Martins DJ, Martins MB, Mazumdar S, McKeown JTA, Anderson-Teixeria K, Miller SE, Milton MA, Miskie R, Morinière J, Mutanen M, Naik S, Nichols B, Noguera FA, Novotny V, Penev L, Pentinsaari M, Quinn J, Ramsay L, Rochefort R, Schmidt S, Smith MA, Sobel CN, Somervuo P, Sones JE, Staude HS, St Jaques B, Stur E, Telfer AC, Tubaro PL, Wardlaw TJ, Worcester R, Yang Z, Young MR, Zemlak T, Zakharov EV, Zlotnick B, Ovaskainen O, Hebert PDN. Seymour M, et al. Among authors: quinn j. Commun Biol. 2024 May 8;7(1):552. doi: 10.1038/s42003-024-06199-1. Commun Biol. 2024. PMID: 38720028 Free PMC article.
3,176 results