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The first-in-class ERK inhibitor ulixertinib shows promising activity in mitogen-activated protein kinase (MAPK)-driven pediatric low-grade glioma models.
Sigaud R, Rösch L, Gatzweiler C, Benzel J, von Soosten L, Peterziel H, Selt F, Najafi S, Ayhan S, Gerloff XF, Hofmann N, Büdenbender I, Schmitt L, Foerster KI, Burhenne J, Haefeli WE, Korshunov A, Sahm F, van Tilburg CM, Jones DTW, Pfister SM, Knoerzer D, Kreider BL, Sauter M, Pajtler KW, Zuckermann M, Oehme I, Witt O, Milde T. Sigaud R, et al. Among authors: rosch l. Neuro Oncol. 2023 Mar 14;25(3):566-579. doi: 10.1093/neuonc/noac183. Neuro Oncol. 2023. PMID: 35882450 Free PMC article.
Combining APR-246 and HDAC-Inhibitors: A Novel Targeted Treatment Option for Neuroblastoma.
Müller M, Rösch L, Najafi S, Gatzweiler C, Ridinger J, Gerloff XF, Jones DTW, Baßler J, Kreth S, Stainczyk S, Frese K, Meder B, Westermann F, Milde T, Peterziel H, Witt O, Oehme I. Müller M, et al. Among authors: rosch l. Cancers (Basel). 2021 Sep 5;13(17):4476. doi: 10.3390/cancers13174476. Cancers (Basel). 2021. PMID: 34503286 Free PMC article.
Multiplexed molecular imaging with surface enhanced resonance Raman scattering nanoprobes reveals immunotherapy response in mice via multichannel image segmentation.
Andreou C, Plakas K, Berisha N, Gigoux M, Rosch LE, Mirsafavi R, Oseledchyk A, Pal S, Zamarin D, Merghoub T, Detty MR, Kircher MF. Andreou C, et al. Among authors: rosch le. Nanoscale Horiz. 2022 Nov 21;7(12):1540-1552. doi: 10.1039/d2nh00331g. Nanoscale Horiz. 2022. PMID: 36285605 Free PMC article.
Design and evaluation of Raman reporters for the Raman-silent region.
Plakas K, Rosch LE, Clark MD, Adbul-Rashed S, Shaffer TM, Harmsen S, Gambhir SS, Detty MR. Plakas K, et al. Among authors: rosch le. Nanotheranostics. 2022 Jan 1;6(1):1-9. doi: 10.7150/ntno.58965. eCollection 2022. Nanotheranostics. 2022. PMID: 34976577 Free PMC article.
11 results