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The NF-κB inhibitor SC75741 efficiently blocks influenza virus propagation and confers a high barrier for development of viral resistance.
Cell Microbiol. 2013 Jul;15(7):1198-211. doi: 10.1111/cmi.12108. Epub 2013 Feb 5.
Cell Microbiol. 2013.
PMID: 23320394
The NS1 protein of influenza A virus blocks RIG-I-mediated activation of the noncanonical NF-κB pathway and p52/RelB-dependent gene expression in lung epithelial cells.
Rückle A, Haasbach E, Julkunen I, Planz O, Ehrhardt C, Ludwig S.
Rückle A, et al.
J Virol. 2012 Sep;86(18):10211-7. doi: 10.1128/JVI.00323-12. Epub 2012 Jul 11.
J Virol. 2012.
PMID: 22787206
Free PMC article.
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The NF-kappaB inhibitor SC75741 protects mice against highly pathogenic avian influenza A virus.
Haasbach E, Reiling SJ, Ehrhardt C, Droebner K, Rückle A, Hrincius ER, Leban J, Strobl S, Vitt D, Ludwig S, Planz O.
Haasbach E, et al. Among authors: ruckle a.
Antiviral Res. 2013 Sep;99(3):336-44. doi: 10.1016/j.antiviral.2013.06.008. Epub 2013 Jun 28.
Antiviral Res. 2013.
PMID: 23811282
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