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Year Number of Results
2016 3
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2020 4
2021 8
2022 1
2023 1
2024 0

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Page 1
Sperm chromatin structure and reproductive fitness are altered by substitution of a single amino acid in mouse protamine 1.
Moritz L, Schon SB, Rabbani M, Sheng Y, Agrawal R, Glass-Klaiber J, Sultan C, Camarillo JM, Clements J, Baldwin MR, Diehl AG, Boyle AP, O'Brien PJ, Ragunathan K, Hu YC, Kelleher NL, Nandakumar J, Li JZ, Orwig KE, Redding S, Hammoud SS. Moritz L, et al. Nat Struct Mol Biol. 2023 Aug;30(8):1077-1091. doi: 10.1038/s41594-023-01033-4. Epub 2023 Jul 17. Nat Struct Mol Biol. 2023. PMID: 37460896 Free PMC article.
Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline.
Graniel JV, Bisht K, Friedman A, White J, Perkey E, Vanderbeck A, Moroz A, Carrington LJ, Brandstadter JD, Allen F, Shami AN, Thomas P, Crayton A, Manzor M, Mychalowych A, Chase J, Hammoud SS, Keegan CE, Maillard I, Nandakumar J. Graniel JV, et al. Life Sci Alliance. 2021 Oct 13;5(1):e202101208. doi: 10.26508/lsa.202101208. Print 2022 Jan. Life Sci Alliance. 2021. PMID: 34645668 Free PMC article.
The clinical and functional effects of TERT variants in myelodysplastic syndrome.
Reilly CR, Myllymäki M, Redd R, Padmanaban S, Karunakaran D, Tesmer V, Tsai FD, Gibson CJ, Rana HQ, Zhong L, Saber W, Spellman SR, Hu ZH, Orr EH, Chen MM, De Vivo I, DeAngelo DJ, Cutler C, Antin JH, Neuberg D, Garber JE, Nandakumar J, Agarwal S, Lindsley RC. Reilly CR, et al. Blood. 2021 Sep 9;138(10):898-911. doi: 10.1182/blood.2021011075. Blood. 2021. PMID: 34019641 Free PMC article. Clinical Trial.
Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity.
Rogawski DS, Deng J, Li H, Miao H, Borkin D, Purohit T, Song J, Chase J, Li S, Ndoj J, Klossowski S, Kim E, Mao F, Zhou B, Ropa J, Krotoska MZ, Jin Z, Ernst P, Feng X, Huang G, Nishioka K, Kelly S, He M, Wen B, Sun D, Muntean A, Dou Y, Maillard I, Cierpicki T, Grembecka J. Rogawski DS, et al. Nat Commun. 2021 May 14;12(1):2792. doi: 10.1038/s41467-021-23152-6. Nat Commun. 2021. PMID: 33990599 Free PMC article.
Molecular mechanisms of telomere biology disorders.
Grill S, Nandakumar J. Grill S, et al. J Biol Chem. 2021 Jan-Jun;296:100064. doi: 10.1074/jbc.REV120.014017. Epub 2020 Nov 22. J Biol Chem. 2021. PMID: 33482595 Free PMC article. Review.
Small Molecules Restore Telomeres in Patient Stem Cells.
Brenner KA, Nandakumar J. Brenner KA, et al. Trends Pharmacol Sci. 2020 Aug;41(8):506-508. doi: 10.1016/j.tips.2020.05.003. Epub 2020 May 29. Trends Pharmacol Sci. 2020. PMID: 32482456 Free PMC article.
25 results