R01 AI129769/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

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Subject: R01 AI129769/AI/NIAID NIH HHS/United States[Grant - PubMed

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Results by year

Year	Number of Results
2016	4
2017	4
2018	5
2019	12
2020	10
2021	8
2022	7
2023	9
2024	1

55 results

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Inhibition of human immunodeficiency virus (HIV-1) infectivity by expression of poorly or broadly neutralizing antibodies against Env in virus-producing cells.

Wang Q, Zhang S, Nguyen HT, Sodroski J. Wang Q, et al. J Virol. 2024 Feb 20;98(2):e0159423. doi: 10.1128/jvi.01594-23. Epub 2024 Jan 30. J Virol. 2024. PMID: 38289101 Free PMC article.

V3 tip determinants of susceptibility to inhibition by CD4-mimetic compounds in natural clade A human immunodeficiency virus (HIV-1) envelope glycoproteins.

Anang S, Zhang S, Fritschi C, Chiu T-J, Yang D, Smith Iii AB, Madani N, Sodroski J. Anang S, et al. J Virol. 2023 Nov 30;97(11):e0117123. doi: 10.1128/jvi.01171-23. Epub 2023 Oct 27. J Virol. 2023. PMID: 37888980 Free PMC article.

Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.

Prévost J, Chen Y, Zhou F, Tolbert WD, Gasser R, Medjahed H, Nayrac M, Nguyen DN, Gottumukkala S, Hessell AJ, Rao VB, Pozharski E, Huang RK, Matthies D, Finzi A, Pazgier M. Prévost J, et al. Nat Commun. 2023 Oct 23;14(1):6710. doi: 10.1038/s41467-023-42500-2. Nat Commun. 2023. PMID: 37872202 Free PMC article.

Temsavir Modulates HIV-1 Envelope Conformation by Decreasing Its Proteolytic Cleavage.

Boutin M, Medjahed H, Nayrac M, Lotke R, Gendron-Lepage G, Bourassa C, Sauter D, Richard J, Finzi A. Boutin M, et al. Viruses. 2023 May 18;15(5):1189. doi: 10.3390/v15051189. Viruses. 2023. PMID: 37243275 Free PMC article.

Piperidine CD4-Mimetic Compounds Expose Vulnerable Env Epitopes Sensitizing HIV-1-Infected Cells to ADCC.

Ding S, Tolbert WD, Zhu H, Lee D, Marchitto L, Higgins T, Zhao X, Nguyen D, Sherburn R, Richard J, Gendron-Lepage G, Medjahed H, Mohammadi M, Abrams C, Pazgier M, Smith AB 3rd, Finzi A. Ding S, et al. Viruses. 2023 May 17;15(5):1185. doi: 10.3390/v15051185. Viruses. 2023. PMID: 37243271 Free PMC article.

Structure-function Analyses Reveal Key Molecular Determinants of HIV-1 CRF01_AE Resistance to the Entry Inhibitor Temsavir.

Prévost J, Chen Y, Zhou F, Tolbert WD, Gasser R, Medjahed H, Gottumukkala S, Hessell AJ, Rao VB, Pozharski E, Huang RK, Matthies D, Finzi A, Pazgier M. Prévost J, et al. bioRxiv [Preprint]. 2023 Apr 17:2023.04.17.537181. doi: 10.1101/2023.04.17.537181. bioRxiv. 2023. PMID: 37131729 Free PMC article. Updated. Preprint.

Piperidine CD4-mimetic compounds expose vulnerable Env epitopes sensitizing HIV-1-infected cells to ADCC.

Ding S, Tolbert WD, Zhu H, Lee D, Higgins T, Zhao X, Nguyen D, Sherburn R, Richard J, Lepage GG, Medjahed H, Mohammadi M, Abrams C, Pazgier M, Smith AB 3rd, Finzi A. Ding S, et al. bioRxiv [Preprint]. 2023 Mar 24:2023.03.23.533923. doi: 10.1101/2023.03.23.533923. bioRxiv. 2023. PMID: 36993184 Free PMC article. Updated. Preprint.

Temsavir blocks the immunomodulatory activities of HIV-1 soluble gp120.

Richard J, Prévost J, Bourassa C, Brassard N, Boutin M, Benlarbi M, Goyette G, Medjahed H, Gendron-Lepage G, Gaudette F, Chen HC, Tolbert WD, Smith AB 3rd, Pazgier M, Dubé M, Clark A, Mothes W, Kaufmann DE, Finzi A. Richard J, et al. Cell Chem Biol. 2023 May 18;30(5):540-552.e6. doi: 10.1016/j.chembiol.2023.03.003. Epub 2023 Mar 22. Cell Chem Biol. 2023. PMID: 36958337 Free article.

Small CD4 mimetics sensitize HIV-1-infected macrophages to antibody-dependent cellular cytotoxicity.

Laumaea A, Marchitto L, Ding S, Beaudoin-Bussières G, Prévost J, Gasser R, Chatterjee D, Gendron-Lepage G, Medjahed H, Chen HC, Smith AB 3rd, Ding H, Kappes JC, Hahn BH, Kirchhoff F, Richard J, Duerr R, Finzi A. Laumaea A, et al. Cell Rep. 2023 Jan 31;42(1):111983. doi: 10.1016/j.celrep.2022.111983. Epub 2023 Jan 10. Cell Rep. 2023. PMID: 36640355 Free PMC article.

Characterization of a Novel CD4 Mimetic Compound YIR-821 against HIV-1 Clinical Isolates.

Matsumoto K, Kuwata T, Tolbert WD, Richard J, Ding S, Prévost J, Takahama S, Judicate GP, Ueno T, Nakata H, Kobayakawa T, Tsuji K, Tamamura H, Smith AB 3rd, Pazgier M, Finzi A, Matsushita S. Matsumoto K, et al. J Virol. 2023 Jan 31;97(1):e0163822. doi: 10.1128/jvi.01638-22. Epub 2022 Dec 13. J Virol. 2023. PMID: 36511698 Free PMC article.

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