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Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases.
Ding Z, Wu CJ, Jaskelioff M, Ivanova E, Kost-Alimova M, Protopopov A, Chu GC, Wang G, Lu X, Labrot ES, Hu J, Wang W, Xiao Y, Zhang H, Zhang J, Zhang J, Gan B, Perry SR, Jiang S, Li L, Horner JW, Wang YA, Chin L, DePinho RA. Ding Z, et al. Cell. 2012 Mar 2;148(5):896-907. doi: 10.1016/j.cell.2012.01.039. Epub 2012 Feb 16. Cell. 2012. PMID: 22341455 Free PMC article.
Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer.
Hu J, Hwang SS, Liesa M, Gan B, Sahin E, Jaskelioff M, Ding Z, Ying H, Boutin AT, Zhang H, Johnson S, Ivanova E, Kost-Alimova M, Protopopov A, Wang YA, Shirihai OS, Chin L, DePinho RA. Hu J, et al. Cell. 2012 Feb 17;148(4):651-63. doi: 10.1016/j.cell.2011.12.028. Cell. 2012. PMID: 22341440 Free PMC article.
Prognostic determinants in prostate cancer.
Martin NE, Mucci LA, Loda M, Depinho RA. Martin NE, et al. Cancer J. 2011 Nov-Dec;17(6):429-37. doi: 10.1097/PPO.0b013e31823b042c. Cancer J. 2011. PMID: 22157287 Free PMC article. Review.