R01 CA123223/CA/NCI NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2009	2
2010	5
2011	5
2012	2
2013	7
2014	5
2015	5
2016	6
2017	1
2018	1
2020	1
2021	1
2023	2
2024	0

1

ROS is a master regulator of in vitro matriptase activation.

Gaymon DO, Barndt R, Stires H, Riggins RB, Johnson MD. Gaymon DO, et al. PLoS One. 2023 Jan 30;18(1):e0267492. doi: 10.1371/journal.pone.0267492. eCollection 2023. PLoS One. 2023. PMID: 36716335 Free PMC article.

2

N-glycosylation on Asn-57 is required for the correct HAI-2 protein folding and protease inhibitory activity.

Huang N, Wang Q, Chen CY, Hu JM, Wang JK, Chang PY, Johnson MD, Lin CY. Huang N, et al. Glycobiology. 2023 Apr 19;33(3):203-214. doi: 10.1093/glycob/cwad002. Glycobiology. 2023. PMID: 36637420 Free PMC article.

3

Plasminogen-Dependent Matriptase Activation Accelerates Plasmin Generation by Differentiating Primary Human Keratinocytes.

Chen YW, Yin S, Lai YJ, Johnson MD, Lin CY. Chen YW, et al. J Invest Dermatol. 2016 Jun;136(6):1210-1218. doi: 10.1016/j.jid.2016.01.029. Epub 2016 Feb 9. J Invest Dermatol. 2016. PMID: 26872599 Free article.

4

Targeted HAI-2 deletion causes excessive proteolysis with prolonged active prostasin and depletion of HAI-1 monomer in intestinal but not epidermal epithelial cells.

Barndt RB, Lee MJ, Huang N, Lu DD, Lee SC, Du PW, Chang CC, Tsai PB, Huang YK, Chang HM, Wang JK, Lai CH, Johnson MD, Lin CY. Barndt RB, et al. Hum Mol Genet. 2021 Sep 15;30(19):1833-1850. doi: 10.1093/hmg/ddab150. Hum Mol Genet. 2021. PMID: 34089062 Free PMC article.

5

Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.

Xu Z, Chen YW, Battu A, Wilder P, Weber D, Yu W, Mackerell AD, Chen LM, Chai KX, Johnson MD, Lin CY. Xu Z, et al. J Med Chem. 2011 Nov 10;54(21):7567-78. doi: 10.1021/jm200920s. Epub 2011 Oct 12. J Med Chem. 2011. PMID: 21966950 Free PMC article.

6

Matriptase autoactivation is tightly regulated by the cellular chemical environments.

Wang JK, Teng IJ, Lo TJ, Moore S, Yeo YH, Teng YC, Kaul M, Chen CC, Zuo AH, Chou FP, Yang X, Tseng IC, Johnson MD, Lin CY. Wang JK, et al. PLoS One. 2014 Apr 4;9(4):e93899. doi: 10.1371/journal.pone.0093899. eCollection 2014. PLoS One. 2014. PMID: 24705933 Free PMC article.

7

Matriptase activation, an early cellular response to acidosis.

Tseng IC, Xu H, Chou FP, Li G, Vazzano AP, Kao JP, Johnson MD, Lin CY. Tseng IC, et al. J Biol Chem. 2010 Jan 29;285(5):3261-70. doi: 10.1074/jbc.M109.055640. Epub 2009 Nov 24. J Biol Chem. 2010. PMID: 19940125 Free PMC article.

8

Matriptase is involved in ErbB-2-induced prostate cancer cell invasion.

Wu SR, Cheng TS, Chen WC, Shyu HY, Ko CJ, Huang HP, Teng CH, Lin CH, Johnson MD, Lin CY, Lee MS. Wu SR, et al. Am J Pathol. 2010 Dec;177(6):3145-58. doi: 10.2353/ajpath.2010.100228. Epub 2010 Oct 22. Am J Pathol. 2010. PMID: 20971737 Free PMC article.

9

The intracellular seven amino acid motif EEGEVFL is required for matriptase vesicle sorting and translocation to the basolateral plasma membrane.

Tseng CC, Jia B, Barndt RB, Dai YH, Chen YH, Du PA, Wang JK, Tang HJ, Lin CY, Johnson MD. Tseng CC, et al. PLoS One. 2020 Feb 12;15(2):e0228874. doi: 10.1371/journal.pone.0228874. eCollection 2020. PLoS One. 2020. PMID: 32049977 Free PMC article.

10

Mechanisms for the control of matriptase activity in the absence of sufficient HAI-1.

Xu H, Xu Z, Tseng IC, Chou FP, Chen YW, Wang JK, Johnson MD, Kataoka H, Lin CY. Xu H, et al. Am J Physiol Cell Physiol. 2012 Jan 15;302(2):C453-62. doi: 10.1152/ajpcell.00344.2011. Epub 2011 Oct 26. Am J Physiol Cell Physiol. 2012. PMID: 22031598 Free PMC article.

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