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Efficiency of bis-amidate phosphonate prodrugs.
Lentini NA, Huang X, Schladetsch MA, Hsiao CC, Wiemer DF, Wiemer AJ. Lentini NA, et al. Bioorg Med Chem Lett. 2022 Jun 15;66:128724. doi: 10.1016/j.bmcl.2022.128724. Epub 2022 Apr 8. Bioorg Med Chem Lett. 2022. PMID: 35405283 Free PMC article.
Stepping forward in antibody-drug conjugate development.
Jin Y, Schladetsch MA, Huang X, Balunas MJ, Wiemer AJ. Jin Y, et al. Pharmacol Ther. 2022 Jan;229:107917. doi: 10.1016/j.pharmthera.2021.107917. Epub 2021 Jun 24. Pharmacol Ther. 2022. PMID: 34171334 Free PMC article. Review.
Incorporation of a FRET pair within a phosphonate diester.
Harmon NM, Huang X, Hsiao CC, Wiemer AJ, Wiemer DF. Harmon NM, et al. Bioorg Chem. 2021 Sep;114:105048. doi: 10.1016/j.bioorg.2021.105048. Epub 2021 May 30. Bioorg Chem. 2021. PMID: 34126576 Free PMC article.
Potent double prodrug forms of synthetic phosphoantigens.
Harmon NM, Huang X, Schladetsch MA, Hsiao CC, Wiemer AJ, Wiemer DF. Harmon NM, et al. Bioorg Med Chem. 2020 Oct 1;28(19):115666. doi: 10.1016/j.bmc.2020.115666. Epub 2020 Jul 29. Bioorg Med Chem. 2020. PMID: 32912439 Free PMC article.
Probing the Ligand-Binding Pocket of BTN3A1.
Poe MM, Agabiti SS, Liu C, Li V, Teske KA, Hsiao CC, Wiemer AJ. Poe MM, et al. J Med Chem. 2019 Jul 25;62(14):6814-6823. doi: 10.1021/acs.jmedchem.9b00825. Epub 2019 Jul 3. J Med Chem. 2019. PMID: 31268699 Free PMC article.
19 results