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Year Number of Results
2019 4
2020 7
2021 5
2022 2
2023 3
2024 1

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Page 1
Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1.
Coleman DJL, Keane P, Chin PS, Ames L, Kellaway S, Blair H, Khan N, Griffin J, Holmes E, Maytum A, Potluri S, Strate L, Koscielniak K, Raghavan M, Bushweller J, Heidenreich O, Rabbitts T, Cockerill PN, Bonifer C. Coleman DJL, et al. iScience. 2024 Mar 26;27(4):109576. doi: 10.1016/j.isci.2024.109576. eCollection 2024 Apr 19. iScience. 2024. PMID: 38638836 Free PMC article.
Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.
Coleman DJL, Keane P, Luque-Martin R, Chin PS, Blair H, Ames L, Kellaway SG, Griffin J, Holmes E, Potluri S, Assi SA, Bushweller J, Heidenreich O, Cockerill PN, Bonifer C. Coleman DJL, et al. bioRxiv [Preprint]. 2023 Jul 19:2023.07.18.549495. doi: 10.1101/2023.07.18.549495. bioRxiv. 2023. PMID: 37503022 Free PMC article. Updated. Preprint.
Allogeneic TCRαβ deficient CAR T-cells targeting CD123 in acute myeloid leukemia.
Sugita M, Galetto R, Zong H, Ewing-Crystal N, Trujillo-Alonso V, Mencia-Trinchant N, Yip W, Filipe S, Lebuhotel C, Gouble A, Hassane DC, Smith J, Roboz GJ, Guzman ML. Sugita M, et al. Nat Commun. 2022 Apr 28;13(1):2227. doi: 10.1038/s41467-022-29668-9. Nat Commun. 2022. PMID: 35484102 Free PMC article.
Patient-Derived Bone Marrow Spheroids Reveal Leukemia-Initiating Cells Supported by Mesenchymal Hypoxic Niches in Pediatric B-ALL.
Balandrán JC, Dávila-Velderrain J, Sandoval-Cabrera A, Zamora-Herrera G, Terán-Cerqueda V, García-Stivalet LA, Limón-Flores JA, Armenta-Castro E, Rodríguez-Martínez A, Leon-Chavez BA, Vallejo-Ruiz V, Hassane DC, Pérez-Tapia SM, Ortiz-Navarrete V, Guzman ML, Pelayo R. Balandrán JC, et al. Front Immunol. 2021 Oct 19;12:746492. doi: 10.3389/fimmu.2021.746492. eCollection 2021. Front Immunol. 2021. PMID: 34737747 Free PMC article.
Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia.
Sugita M, Wilkes DC, Bareja R, Eng KW, Nataraj S, Jimenez-Flores RA, Yan L, De Leon JP, Croyle JA, Kaner J, Merugu S, Sharma S, MacDonald TY, Noorzad Z, Panchal P, Pancirer D, Cheng S, Xiang JZ, Olson L, Van Besien K, Rickman DS, Mathew S, Tam W, Rubin MA, Beltran H, Sboner A, Hassane DC, Chiosis G, Elemento O, Roboz GJ, Mosquera JM, Guzman ML. Sugita M, et al. NPJ Precis Oncol. 2021 May 26;5(1):44. doi: 10.1038/s41698-021-00183-2. NPJ Precis Oncol. 2021. PMID: 34040147 Free PMC article.
Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators.
O'Hare M, Amarnani D, Whitmore HAB, An M, Marino C, Ramos L, Delgado-Tirado S, Hu X, Chmielewska N, Chandrahas A, Fitzek A, Heinrich F, Steurer S, Ondruschka B, Glatzel M, Krasemann S, Sepulveda-Falla D, Lagares D, Pedron J, Bushweller JH, Liu P, Arboleda-Velasquez JF, Kim LA. O'Hare M, et al. Am J Pathol. 2021 Jul;191(7):1193-1208. doi: 10.1016/j.ajpath.2021.04.006. Epub 2021 Apr 21. Am J Pathol. 2021. PMID: 33894177 Free PMC article.
TNF-α signaling regulates RUNX1 function in endothelial cells.
Whitmore HAB, Amarnani D, O'Hare M, Delgado-Tirado S, Gonzalez-Buendia L, An M, Pedron J, Bushweller JH, Arboleda-Velasquez JF, Kim LA. Whitmore HAB, et al. FASEB J. 2021 Feb;35(2):e21155. doi: 10.1096/fj.202001668R. Epub 2020 Nov 2. FASEB J. 2021. PMID: 33135824 Free PMC article.
20 results