Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2020 1
2021 1
2022 4
2023 2
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

7 results

Results by year

Filters applied: . Clear all
Page 1
Discovery and Evaluation of C6-Substituted Pyrazolopyrimidine-Based Bisphosphonate Inhibitors of the Human Geranylgeranyl Pyrophosphate Synthase and Evaluation of Their Antitumor Efficacy in Multiple Myeloma, Pancreatic Ductal Adenocarcinoma, and Colorectal Cancer.
Boutin R, Lee HF, Guan TL, Nguyen TT, Huang XF, Waller DD, Lu J, Christine Chio II, Michel RP, Sebag M, Tsantrizos YS. Boutin R, et al. J Med Chem. 2023 Dec 14;66(23):15776-15800. doi: 10.1021/acs.jmedchem.3c01271. Epub 2023 Nov 20. J Med Chem. 2023. PMID: 37982711 Free PMC article.
Inactivation of Notch4 Attenuated Pancreatic Tumorigenesis in Mice.
Saeki K, Qiu W, Friedman RA, Pan S, Lu J, Ichimiya S, Chio IIC, Shawber CJ, Kitajewski J, Hu J, Su GH. Saeki K, et al. Cancer Res Commun. 2022 Dec 12;2(12):1601-1616. doi: 10.1158/2767-9764.CRC-22-0106. eCollection 2022 Dec. Cancer Res Commun. 2022. PMID: 36970723 Free PMC article.
A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma.
Zhou RW, Xu J, Martin TC, Zachem AL, He J, Ozturk S, Demircioglu D, Bansal A, Trotta AP, Giotti B, Gryder B, Shen Y, Wu X, Carcamo S, Bosch K, Hopkins B, Tsankov A, Steinhagen R, Jones DR, Asara J, Chipuk JE, Brody R, Itzkowitz S, Chio IIC, Hasson D, Bernstein E, Parsons RE. Zhou RW, et al. Nat Commun. 2022 Oct 17;13(1):6041. doi: 10.1038/s41467-022-33377-8. Nat Commun. 2022. PMID: 36253360 Free PMC article.
Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis.
He D, Feng H, Sundberg B, Yang J, Powers J, Christian AH, Wilkinson JE, Monnin C, Avizonis D, Thomas CJ, Friedman RA, Kluger MD, Hollingsworth MA, Grandgenett PM, Klute KA, Toste FD, Chang CJ, Chio IIC. He D, et al. Mol Cell. 2022 Aug 18;82(16):3045-3060.e11. doi: 10.1016/j.molcel.2022.06.005. Epub 2022 Jun 24. Mol Cell. 2022. PMID: 35752173 Free PMC article.
Softening redox homeostasis in cancer cells.
Powers JA, Chio IIC. Powers JA, et al. Nat Cell Biol. 2022 Feb;24(2):133-134. doi: 10.1038/s41556-022-00845-8. Nat Cell Biol. 2022. PMID: 35165419 Free PMC article.
PDA Got SERious Nerves.
Yang X, Chio IIC. Yang X, et al. Trends Cancer. 2021 Feb;7(2):89-91. doi: 10.1016/j.trecan.2020.12.004. Epub 2020 Dec 16. Trends Cancer. 2021. PMID: 33341431 Free PMC article.