R01 DK057699/DK/NIDDK NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2001	2
2002	3
2003	2
2004	2
2005	3
2006	3
2007	1
2008	1
2009	2
2010	2
2011	4
2012	4
2013	7
2014	2
2015	3
2016	1
2017	2
2018	1
2019	5
2020	3
2021	2
2022	2
2024	0

1

Localized islet nuclear enlargement hyperinsulinism (LINE-HI) due to ABCC8 and GCK mosaic mutations.

Boodhansingh KE, Yang Z, Li C, Chen P, Lord K, Becker SA, States LJ, Adzick NS, Bhatti T, Shyng SL, Ganguly A, Stanley CA, De Leon DD. Boodhansingh KE, et al. Eur J Endocrinol. 2022 Jun 27;187(2):301-313. doi: 10.1530/EJE-21-1095. Print 2022 Aug 1. Eur J Endocrinol. 2022. PMID: 35674212 Free PMC article.

2

Subcellular trafficking and endocytic recycling of K_ATP channels.

Yang HQ, Echeverry FA, ElSheikh A, Gando I, Anez Arredondo S, Samper N, Cardozo T, Delmar M, Shyng SL, Coetzee WA. Yang HQ, et al. Am J Physiol Cell Physiol. 2022 Jun 1;322(6):C1230-C1247. doi: 10.1152/ajpcell.00099.2022. Epub 2022 May 4. Am J Physiol Cell Physiol. 2022. PMID: 35508187 Free PMC article. Review.

3

AKAP79/150 coordinates leptin-induced PKA signaling to regulate K_ATP channel trafficking in pancreatic β-cells.

Cochrane VA, Yang Z, Dell'Acqua ML, Shyng SL. Cochrane VA, et al. J Biol Chem. 2021 Jan-Jun;296:100442. doi: 10.1016/j.jbc.2021.100442. Epub 2021 Feb 19. J Biol Chem. 2021. PMID: 33617875 Free PMC article.

4

Functional characterization of ABCC8 variants of unknown significance based on bioinformatics predictions, splicing assays, and protein analyses: Benefits for the accurate diagnosis of congenital hyperinsulinism.

Saint-Martin C, Cauchois-Le Mière M, Rex E, Soukarieh O, Arnoux JB, Buratti J, Bouvet D, Frébourg T, Gaildrat P, Shyng SL, Bellanné-Chantelot C, Martins A. Saint-Martin C, et al. Hum Mutat. 2021 Apr;42(4):408-420. doi: 10.1002/humu.24164. Epub 2021 Jan 28. Hum Mutat. 2021. PMID: 33410562 Free PMC article.

5

Leptin modulates pancreatic β-cell membrane potential through Src kinase-mediated phosphorylation of NMDA receptors.

Cochrane VA, Wu Y, Yang Z, ElSheikh A, Dunford J, Kievit P, Fortin DA, Shyng SL. Cochrane VA, et al. J Biol Chem. 2020 Dec 11;295(50):17281-17297. doi: 10.1074/jbc.RA120.015489. Epub 2020 Oct 9. J Biol Chem. 2020. PMID: 33037073 Free PMC article.

6

Pharmacological chaperones of ATP-sensitive potassium channels: Mechanistic insight from cryoEM structures.

Martin GM, Sung MW, Shyng SL. Martin GM, et al. Mol Cell Endocrinol. 2020 Feb 15;502:110667. doi: 10.1016/j.mce.2019.110667. Epub 2019 Dec 9. Mol Cell Endocrinol. 2020. PMID: 31821855 Free PMC article. Review.

7

Ion Channels of the Islets in Type 2 Diabetes.

Jacobson DA, Shyng SL. Jacobson DA, et al. J Mol Biol. 2020 Mar 6;432(5):1326-1346. doi: 10.1016/j.jmb.2019.08.014. Epub 2019 Aug 30. J Mol Biol. 2020. PMID: 31473158 Free PMC article. Review.

8

Novel dominant K_ATP channel mutations in infants with congenital hyperinsulinism: Validation by in vitro expression studies and in vivo carrier phenotyping.

Boodhansingh KE, Kandasamy B, Mitteer L, Givler S, De Leon DD, Shyng SL, Ganguly A, Stanley CA. Boodhansingh KE, et al. Am J Med Genet A. 2019 Nov;179(11):2214-2227. doi: 10.1002/ajmg.a.61335. Epub 2019 Aug 28. Am J Med Genet A. 2019. PMID: 31464105 Free PMC article.

9

Mechanism of pharmacochaperoning in a mammalian K_ATP channel revealed by cryo-EM.

Martin GM, Sung MW, Yang Z, Innes LM, Kandasamy B, David LL, Yoshioka C, Shyng SL. Martin GM, et al. Elife. 2019 Jul 25;8:e46417. doi: 10.7554/eLife.46417. Elife. 2019. PMID: 31343405 Free PMC article.

10

Leptin-induced Trafficking of K_ATP Channels: A Mechanism to Regulate Pancreatic β-cell Excitability and Insulin Secretion.

Cochrane V, Shyng SL. Cochrane V, et al. Int J Mol Sci. 2019 May 30;20(11):2660. doi: 10.3390/ijms20112660. Int J Mol Sci. 2019. PMID: 31151172 Free PMC article. Review.

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