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Mito-metformin protects against mitochondrial dysfunction and dopaminergic neuronal degeneration by activating upstream PKD1 signaling in cell culture and MitoPark animal models of Parkinson's disease.
Ay M, Charli A, Langley M, Jang A, Padhi P, Jin H, Anantharam V, Kalyanaraman B, Kanthasamy A, Kanthasamy AG. Ay M, et al. Front Neurosci. 2024 Feb 21;18:1356703. doi: 10.3389/fnins.2024.1356703. eCollection 2024. Front Neurosci. 2024. PMID: 38449738 Free PMC article.
Environmental neurotoxic pesticide exposure induces gut inflammation and enteric neuronal degeneration by impairing enteric glial mitochondrial function in pesticide models of Parkinson's disease: Potential relevance to gut-brain axis inflammation in Parkinson's disease pathogenesis.
Palanisamy BN, Sarkar S, Malovic E, Samidurai M, Charli A, Zenitsky G, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG. Palanisamy BN, et al. Int J Biochem Cell Biol. 2022 Jun;147:106225. doi: 10.1016/j.biocel.2022.106225. Epub 2022 May 12. Int J Biochem Cell Biol. 2022. PMID: 35550926 Free PMC article.
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