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A novel dopamine D3R agonist SK609 with norepinephrine transporter inhibition promotes improvement in cognitive task performance in rodent and non-human primate models of Parkinson's disease.
Schneider JS, Marshall CA, Keibel L, Snyder NW, Hill MP, Brotchie JM, Johnston TH, Waterhouse BD, Kortagere S. Schneider JS, et al. Exp Neurol. 2021 Jan;335:113514. doi: 10.1016/j.expneurol.2020.113514. Epub 2020 Oct 22. Exp Neurol. 2021. PMID: 33141071 Free PMC article.
Identification of a Novel Allosteric Modulator of the Human Dopamine Transporter.
Aggarwal S, Liu X, Rice C, Menell P, Clark PJ, Paparoidamis N, Xiao YC, Salvino JM, Fontana ACK, España RA, Kortagere S, Mortensen OV. Aggarwal S, et al. ACS Chem Neurosci. 2019 Aug 21;10(8):3718-3730. doi: 10.1021/acschemneuro.9b00262. Epub 2019 Jun 24. ACS Chem Neurosci. 2019. PMID: 31184115 Free PMC article.
Overview of Monoamine Transporters.
Aggarwal S, Mortensen OV. Aggarwal S, et al. Curr Protoc Pharmacol. 2017 Dec 20;79:12.16.1-12.16.17. doi: 10.1002/cpph.32. Curr Protoc Pharmacol. 2017. PMID: 29261228 Free PMC article. Review.
11 results