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oFlowSeq: a quantitative approach to identify protein coding mutations affecting cell type enrichment using mosaic CRISPR-Cas9 edited cerebral organoids.
Dawes P, Murray LF, Olson MN, Barton NJ, Smullen M, Suresh M, Yan G, Zhang Y, Fernandez-Fontaine A, English J, Uddin M, Pak C, Church GM, Chan Y, Lim ET. Dawes P, et al. Hum Genet. 2023 Aug;142(8):1281-1291. doi: 10.1007/s00439-023-02534-4. Epub 2023 Mar 6. Hum Genet. 2023. PMID: 36877372 Free PMC article.
Analyses of the autism-associated neuroligin-3 R451C mutation in human neurons reveal a gain-of-function synaptic mechanism.
Wang L, Mirabella VR, Dai R, Su X, Xu R, Jadali A, Bernabucci M, Singh I, Chen Y, Tian J, Jiang P, Kwan KY, Pak C, Liu C, Comoletti D, Hart RP, Chen C, Südhof TC, Pang ZP. Wang L, et al. Mol Psychiatry. 2022 Oct 24:10.1038/s41380-022-01834-x. doi: 10.1038/s41380-022-01834-x. Online ahead of print. Mol Psychiatry. 2022. PMID: 36280753 Free PMC article.
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