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Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease.
Lee DW, Rajagopalan S, Siddiq A, Gwiazda R, Yang L, Beal MF, Ratan RR, Andersen JK. Lee DW, et al. J Biol Chem. 2009 Oct 16;284(42):29065-76. doi: 10.1074/jbc.M109.000638. Epub 2009 Aug 13. J Biol Chem. 2009. PMID: 19679656 Free PMC article.
A disruption in iron-sulfur center biogenesis via inhibition of mitochondrial dithiol glutaredoxin 2 may contribute to mitochondrial and cellular iron dysregulation in mammalian glutathione-depleted dopaminergic cells: implications for Parkinson's disease.
Lee DW, Kaur D, Chinta SJ, Rajagopalan S, Andersen JK. Lee DW, et al. Antioxid Redox Signal. 2009 Sep;11(9):2083-94. doi: 10.1089/ars.2009.2489. Antioxid Redox Signal. 2009. PMID: 19290777 Free PMC article.