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2015 1
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Minimizing higher-order aggregation maximizes iron mobilization by small molecules.
Blake AD, Chao J, SantaMaria AM, Ekaputri S, Green KJ, Brown ST, Rakowski CK, Choi EK, Aring L, Chen PJ, Snead NM, Matje DM, Geng T, Octaviani A, Bailey K, Hollenbach SJ, Fan TM, Seo YA, Burke MD. Blake AD, et al. Nat Chem Biol. 2024 Apr 25. doi: 10.1038/s41589-024-01596-3. Online ahead of print. Nat Chem Biol. 2024. PMID: 38664586
The fatty liver disease-causing protein PNPLA3-I148M alters lipid droplet-Golgi dynamics.
Sherman DJ, Liu L, Mamrosh JL, Xie J, Ferbas J, Lomenick B, Ladinsky MS, Verma R, Rulifson IC, Deshaies RJ. Sherman DJ, et al. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2318619121. doi: 10.1073/pnas.2318619121. Epub 2024 Apr 24. Proc Natl Acad Sci U S A. 2024. PMID: 38657050
To identify their intracellular associations, we generated a paired set of isogenic human hepatoma cells expressing PNPLA3 and PNPLA3-I148M at endogenous levels. ...Cumulatively, we validate an endogenous human cellular system for investigating PNPLA3-I148M biology …
To identify their intracellular associations, we generated a paired set of isogenic human hepatoma cells expressing PNPLA3 and PNPLA3 …
Identification of the potassium-binding site in serotonin transporter.
Hellsberg E, Boytsov D, Chen Q, Niello M, Freissmuth M, Rudnick G, Zhang YW, Sandtner W, Forrest LR. Hellsberg E, et al. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2319384121. doi: 10.1073/pnas.2319384121. Epub 2024 Apr 23. Proc Natl Acad Sci U S A. 2024. PMID: 38652746
1,837 results