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Genetic tools for the stable overexpression of circular RNAs.
Mecozzi N, Nenci A, Vera O, Bok I, Falzone A, DeNicola GM, Karreth FA. Mecozzi N, et al. RNA Biol. 2022;19(1):353-363. doi: 10.1080/15476286.2022.2043041. Epub 2021 Dec 31. RNA Biol. 2022. PMID: 35289721 Free PMC article.
A MAPK/miR-29 Axis Suppresses Melanoma by Targeting MAFG and MYBL2.
Vera O, Bok I, Jasani N, Nakamura K, Xu X, Mecozzi N, Angarita A, Wang K, Tsai KY, Karreth FA. Vera O, et al. Cancers (Basel). 2021 Mar 19;13(6):1408. doi: 10.3390/cancers13061408. Cancers (Basel). 2021. PMID: 33808771 Free PMC article.
Melanoma models for the next generation of therapies.
Patton EE, Mueller KL, Adams DJ, Anandasabapathy N, Aplin AE, Bertolotto C, Bosenberg M, Ceol CJ, Burd CE, Chi P, Herlyn M, Holmen SL, Karreth FA, Kaufman CK, Khan S, Kobold S, Leucci E, Levy C, Lombard DB, Lund AW, Marie KL, Marine JC, Marais R, McMahon M, Robles-Espinoza CD, Ronai ZA, Samuels Y, Soengas MS, Villanueva J, Weeraratna AT, White RM, Yeh I, Zhu J, Zon LI, Hurlbert MS, Merlino G. Patton EE, et al. Cancer Cell. 2021 May 10;39(5):610-631. doi: 10.1016/j.ccell.2021.01.011. Epub 2021 Feb 4. Cancer Cell. 2021. PMID: 33545064 Free PMC article. Review.
PHGDH supports liver ceramide synthesis and sustains lipid homeostasis.
Kang YP, Falzone A, Liu M, González-Sánchez P, Choi BH, Coloff JL, Saller JJ, Karreth FA, DeNicola GM. Kang YP, et al. Cancer Metab. 2020 Jun 15;8:6. doi: 10.1186/s40170-020-00212-x. eCollection 2020. Cancer Metab. 2020. PMID: 32549981 Free PMC article.
A Versatile ES Cell-Based Melanoma Mouse Modeling Platform.
Bok I, Vera O, Xu X, Jasani N, Nakamura K, Reff J, Nenci A, Gonzalez JG, Karreth FA. Bok I, et al. Cancer Res. 2020 Feb 15;80(4):912-921. doi: 10.1158/0008-5472.CAN-19-2924. Epub 2019 Nov 19. Cancer Res. 2020. PMID: 31744817 Free PMC article.