R37 GM027757/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
1998	1
2000	2
2001	2
2002	1
2003	2
2004	4
2005	2
2006	2
2007	3
2008	2
2009	2
2010	4
2012	3
2013	4
2014	4
2015	5
2016	2
2017	1
2018	3
2019	1
2024	0

1

New in Vitro Assay Measuring Direct Interaction of Nonsense Suppressors with the Eukaryotic Protein Synthesis Machinery.

Ng MY, Zhang H, Weil A, Singh V, Jamiolkowski R, Baradaran-Heravi A, Roberge M, Jacobson A, Friesen W, Welch E, Goldman YE, Cooperman BS. Ng MY, et al. ACS Med Chem Lett. 2018 Nov 21;9(12):1285-1291. doi: 10.1021/acsmedchemlett.8b00472. eCollection 2018 Dec 13. ACS Med Chem Lett. 2018. PMID: 30613341 Free PMC article.

2

Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo.

Zeidan Q, He F, Zhang F, Zhang H, Jacobson A, Hinnebusch AG. Zeidan Q, et al. PLoS Genet. 2018 Dec 7;14(12):e1007806. doi: 10.1371/journal.pgen.1007806. eCollection 2018 Dec. PLoS Genet. 2018. PMID: 30532217 Free PMC article.

3

Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties.

Cao L, Weetall M, Trotta C, Cintron K, Ma J, Kim MJ, Furia B, Romfo C, Graci JD, Li W, Du J, Sheedy J, Hedrick J, Risher N, Yeh S, Qi H, Arasu T, Hwang S, Lennox W, Kong R, Petruska J, Moon YC, Babiak J, Davis TW, Jacobson A, Almstead NG, Branstrom A, Colacino JM, Peltz SW. Cao L, et al. Mol Cancer Ther. 2019 Jan;18(1):3-16. doi: 10.1158/1535-7163.MCT-18-0863. Epub 2018 Oct 23. Mol Cancer Ther. 2019. PMID: 30352802 Free PMC article.

4

The moment when translational control had a theory of everything.

Jacobson A. Jacobson A. Nat Rev Mol Cell Biol. 2017 Jun;18(6):344. doi: 10.1038/nrm.2017.33. Epub 2017 Apr 12. Nat Rev Mol Cell Biol. 2017. PMID: 28400611 Review. No abstract available.

5

Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression.

Roy B, Friesen WJ, Tomizawa Y, Leszyk JD, Zhuo J, Johnson B, Dakka J, Trotta CR, Xue X, Mutyam V, Keeling KM, Mobley JA, Rowe SM, Bedwell DM, Welch EM, Jacobson A. Roy B, et al. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12508-12513. doi: 10.1073/pnas.1605336113. Epub 2016 Oct 4. Proc Natl Acad Sci U S A. 2016. PMID: 27702906 Free PMC article.

6

Correction: Degradation of YRA1 Pre-mRNA in the Cytoplasm Requires Translational Repression, Multiple Modular Intronic Elements, Edc3p, and Mex67p.

Dong S, Jacobson A, He F. Dong S, et al. PLoS Biol. 2016 May 12;14(5):e1002470. doi: 10.1371/journal.pbio.1002470. eCollection 2016 May. PLoS Biol. 2016. PMID: 27171161 Free PMC article.

7

Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story.

He F, Jacobson A. He F, et al. Annu Rev Genet. 2015;49:339-66. doi: 10.1146/annurev-genet-112414-054639. Epub 2015 Oct 2. Annu Rev Genet. 2015. PMID: 26436458 Free PMC article. Review.

8

Control of mRNA decapping by positive and negative regulatory elements in the Dcp2 C-terminal domain.

He F, Jacobson A. He F, et al. RNA. 2015 Sep;21(9):1633-47. doi: 10.1261/rna.052449.115. Epub 2015 Jul 16. RNA. 2015. PMID: 26184073 Free PMC article.

9

Methods to our madness.

Jacobson A. Jacobson A. RNA. 2015 Apr;21(4):529-30. doi: 10.1261/rna.049684.115. RNA. 2015. PMID: 25780125 Free PMC article. No abstract available.

10

Nonsense suppression by near-cognate tRNAs employs alternative base pairing at codon positions 1 and 3.

Roy B, Leszyk JD, Mangus DA, Jacobson A. Roy B, et al. Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):3038-43. doi: 10.1073/pnas.1424127112. Epub 2015 Mar 2. Proc Natl Acad Sci U S A. 2015. PMID: 25733896 Free PMC article.

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