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Page 1
Methylsulfonylnitrobenzoates, a new class of irreversible inhibitors of the interaction of the thyroid hormone receptor and its obligate coactivators that functionally antagonizes thyroid hormone.
Hwang JY, Huang W, Arnold LA, Huang R, Attia RR, Connelly M, Wichterman J, Zhu F, Augustinaite I, Austin CP, Inglese J, Johnson RL, Guy RK. Hwang JY, et al. J Biol Chem. 2011 Apr 8;286(14):11895-908. doi: 10.1074/jbc.M110.200436. Epub 2011 Feb 14. J Biol Chem. 2011. PMID: 21321127 Free PMC article.
A surface on the androgen receptor that allosterically regulates coactivator binding.
Estébanez-Perpiñá E, Arnold LA, Nguyen P, Rodrigues ED, Mar E, Bateman R, Pallai P, Shokat KM, Baxter JD, Guy RK, Webb P, Fletterick RJ. Estébanez-Perpiñá E, et al. Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16074-9. doi: 10.1073/pnas.0708036104. Epub 2007 Oct 2. Proc Natl Acad Sci U S A. 2007. PMID: 17911242 Free PMC article.
Quantification of the vitamin D receptor-coregulator interaction.
Teichert A, Arnold LA, Otieno S, Oda Y, Augustinaite I, Geistlinger TR, Kriwacki RW, Guy RK, Bikle DD. Teichert A, et al. Biochemistry. 2009 Feb 24;48(7):1454-61. doi: 10.1021/bi801874n. Biochemistry. 2009. PMID: 19183053 Free PMC article.
Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells.
De Leon JT, Iwai A, Feau C, Garcia Y, Balsiger HA, Storer CL, Suro RM, Garza KM, Lee S, Kim YS, Chen Y, Ning YM, Riggs DL, Fletterick RJ, Guy RK, Trepel JB, Neckers LM, Cox MB. De Leon JT, et al. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11878-83. doi: 10.1073/pnas.1105160108. Epub 2011 Jul 5. Proc Natl Acad Sci U S A. 2011. PMID: 21730179 Free PMC article.
11 results