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Delving into the Heterogeneity of Different Breast Cancer Subtypes and the Prognostic Models Utilizing scRNA-Seq and Bulk RNA-Seq.
Xu J, Qin S, Yi Y, Gao H, Liu X, Ma F, Guan M. Xu J, et al. Int J Mol Sci. 2022 Sep 1;23(17):9936. doi: 10.3390/ijms23179936. Int J Mol Sci. 2022. PMID: 36077333 Free PMC article.
BACKGROUND: Breast cancer (BC) is the most common malignancy in women with high heterogeneity. ...METHODS: Cancer cells were identified by calculating single cell copy number variation using the inferCNV algorithm. ...
BACKGROUND: Breast cancer (BC) is the most common malignancy in women with high heterogeneity. ...METHODS: Cancer cells were i …
Ribosomal protein L31 (RPL31) inhibits the proliferation and migration of gastric cancer cells.
Wu F, Liu Y, Hu S, Lu C. Wu F, et al. Heliyon. 2023 Jan 20;9(2):e13076. doi: 10.1016/j.heliyon.2023.e13076. eCollection 2023 Feb. Heliyon. 2023. PMID: 36816257 Free PMC article.
Aberrant expression of Ribosomal Protein L31 (RPL31) has been reported in several human cancers. The aim of this study was to explore the role and possible biological functions of RPL31 in GC. We firstly employed immunohistochemistry to examine RPL31 e …
Aberrant expression of Ribosomal Protein L31 (RPL31) has been reported in several human cancers. The aim of this study was to …
ScRNA-seq revealed an immunosuppression state and tumor microenvironment heterogeneity related to lymph node metastasis in prostate cancer.
Xin S, Liu X, Li Z, Sun X, Wang R, Zhang Z, Feng X, Jin L, Li W, Tang C, Mei W, Cao Q, Wang H, Zhang J, Feng L, Ye L. Xin S, et al. Exp Hematol Oncol. 2023 May 23;12(1):49. doi: 10.1186/s40164-023-00407-0. Exp Hematol Oncol. 2023. PMID: 37221625 Free PMC article.
BACKGROUND: Metastasis is a crucial aspect of disease progression leading to death in patients with prostate cancer (PCa). However, its mechanism remains unclear. We aimed to explore the mechanism of lymph node metastasis (LNM) by analyzing the heterogeneity of tumor micro …
BACKGROUND: Metastasis is a crucial aspect of disease progression leading to death in patients with prostate cancer (PCa). However, i …
Diamond-Blackfan Anemia.
Sieff C. Sieff C. 2009 Jun 25 [updated 2023 Mar 23]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2009 Jun 25 [updated 2023 Mar 23]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301769 Free Books & Documents. Review.
Evaluation by an endocrinologist for those who are steroid dependent and those at risk for transfusion iron overload. Cancer surveillance includes history, physical examination, and blood counts every four to six months. ...Evaluation of relatives at risk: Molecular geneti …
Evaluation by an endocrinologist for those who are steroid dependent and those at risk for transfusion iron overload. Cancer surveill …
Expression, purification, and evaluation for anticancer activity of ribosomal protein L31 gene (RPL31) from the giant panda (Ailuropoda melanoleuca).
Su XL, Hou YL, Yan XH, Ding X, Hou WR, Sun B, Zhang SN. Su XL, et al. Mol Biol Rep. 2012 Sep;39(9):8945-54. doi: 10.1007/s11033-012-1763-0. Epub 2012 Jun 20. Mol Biol Rep. 2012. PMID: 22714919
The expression product was purified to obtain recombinant protein of RPL31 from the giant panda. Recombinant protein of RPL31 obtained from the experiment acted on human laryngeal carcinoma Hep-2 and human hepatoma HepG-2 cells for study of its anti-cancer ac …
The expression product was purified to obtain recombinant protein of RPL31 from the giant panda. Recombinant protein of RPL31
Short hairpin RNA library-based functional screening identified ribosomal protein L31 that modulates prostate cancer cell growth via p53 pathway.
Maruyama Y, Miyazaki T, Ikeda K, Okumura T, Sato W, Horie-Inoue K, Okamoto K, Takeda S, Inoue S. Maruyama Y, et al. PLoS One. 2014 Oct 6;9(10):e108743. doi: 10.1371/journal.pone.0108743. eCollection 2014. PLoS One. 2014. PMID: 25285958 Free PMC article.
Of note, RPL31 mRNA is more abundantly expressed in BicR cells than in parental LNCaP cells, and clinical data from ONCOMINE and The Cancer Genome Altas showed that RPL31 is overexpressed in prostate carcinomas compared with benign prostate tissues. ...These …
Of note, RPL31 mRNA is more abundantly expressed in BicR cells than in parental LNCaP cells, and clinical data from ONCOMINE and The …
RPL34-AS1 functions as tumor suppressive lncRNA in esophageal cancer.
Gong Z, Li J, Cang P, Jiang H, Liang J, Hou Y. Gong Z, et al. Biomed Pharmacother. 2019 Dec;120:109440. doi: 10.1016/j.biopha.2019.109440. Epub 2019 Sep 28. Biomed Pharmacother. 2019. PMID: 31574377 Free article.
Ribosomal protein L34 antisense RNA 1 (RPL34-AS1) is novel long non-coding RNA, and was found to be down-regulated in colorectal cancer and gastric cancer. ...In conclusion, RPL34-AS1 functions as tumor suppressor in esophageal cancer....
Ribosomal protein L34 antisense RNA 1 (RPL34-AS1) is novel long non-coding RNA, and was found to be down-regulated in c
Silencing eL31 suppresses the progression of colorectal cancer via targeting DEPDC1.
Sharen G, Li X, Sun J, Zhang L, Xi W, Zhao X, Han F, Jia L, A R, Cheng H, Hou M. Sharen G, et al. J Transl Med. 2022 Oct 29;20(1):493. doi: 10.1186/s12967-022-03663-6. J Transl Med. 2022. PMID: 36309731 Free PMC article.
BACKGROUND: Colorectal cancer (CRC) is one of the most commonly diagnosed human malignancies. Ribosomal protein L31 (RPL31, aka eL31) is a component of the 60S large ribosomal subunit, and its expression pattern and functional role in CRC have not been reported. ...
BACKGROUND: Colorectal cancer (CRC) is one of the most commonly diagnosed human malignancies. Ribosomal protein L31 (RPL31, ak …
Integrated Multi-Omics Analysis Model to Identify Biomarkers Associated With Prognosis of Breast Cancer.
Fan Y, Kao C, Yang F, Wang F, Yin G, Wang Y, He Y, Ji J, Liu L. Fan Y, et al. Front Oncol. 2022 Jun 10;12:899900. doi: 10.3389/fonc.2022.899900. eCollection 2022. Front Oncol. 2022. PMID: 35761863 Free PMC article.
The TCGA and METABRIC database were used as the training and validation set respectively. RESULT: In the TCGA dataset, C11orf1, OLA1, RPL31, SPDL1 and IL33 were identified to be associated with prognosis of breast cancer. ...CONCLUSION: In this study, a total of 15 …
The TCGA and METABRIC database were used as the training and validation set respectively. RESULT: In the TCGA dataset, C11orf1, OLA1, RPL
Artificial Downregulation of Ribosomal Protein L34 Restricts the Proliferation and Metastasis of Colorectal Cancer by Suppressing the JAK2/STAT3 Signaling Pathway.
Liang YC, Li R, Bao SR, Li ZL, Yin HZ, Dai CL. Liang YC, et al. Hum Gene Ther. 2023 Aug;34(15-16):719-731. doi: 10.1089/hum.2023.046. Hum Gene Ther. 2023. PMID: 37427415
The highly conserved ribosomal protein L34 (RPL34) has been reported to play an essential role in the progression of diverse malignancies. RPL34 is aberrantly expressed in multiple cancers, although its significant in colorectal cancer (CRC) is …
The highly conserved ribosomal protein L34 (RPL34) has been reported to play an essential role in the progression of di …
28 results