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Year Number of Results
2001 1
2002 1
2003 3
2004 3
2005 2
2006 4
2007 3
2008 1
2009 4
2010 1
2011 6
2012 5
2013 6
2014 8
2015 7
2016 7
2017 4
2018 7
2019 4
2021 3
2022 9
2023 8
2024 0

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88 results

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Page 1
CircRTN4 promotes pancreatic cancer progression through a novel CircRNA-miRNA-lncRNA pathway and stabilizing epithelial-mesenchymal transition protein.
Wong CH, Lou UK, Fung FK, Tong JHM, Zhang CH, To KF, Chan SL, Chen Y. Wong CH, et al. Mol Cancer. 2022 Jan 4;21(1):10. doi: 10.1186/s12943-021-01481-w. Mol Cancer. 2022. PMID: 34983537 Free PMC article.
However, the detailed mechanism underlying the critical roles of circRNAs in cancer remains largely unexplored. We aim to explore the molecular mechanisms of circRTN4 with critical roles in pancreatic ductal adenocarcinoma (PDAC). ...
However, the detailed mechanism underlying the critical roles of circRNAs in cancer remains largely unexplored. We aim to explore the …
RTN4/Nogo is an independent prognostic marker for gastric cancer: preliminary results.
Chi C, Liu N, Yue L, Qi WW, Xu LL, Qiu WS. Chi C, et al. Eur Rev Med Pharmacol Sci. 2015;19(2):241-6. Eur Rev Med Pharmacol Sci. 2015. PMID: 25683937 Free article.
In Cox multivariate analysis, high RTN4 (p = 0.0160) is an independent prognostic factor for overall survival of gastric cancer patients. CONCLUSIONS: Our data suggest that RTN4 may contribute to the malignant progression of gastric cancer and serve as …
In Cox multivariate analysis, high RTN4 (p = 0.0160) is an independent prognostic factor for overall survival of gastric cancer …
RTN4 Knockdown Dysregulates the AKT Pathway, Destabilizes the Cytoskeleton, and Enhances Paclitaxel-Induced Cytotoxicity in Cancers.
Pathak GP, Shah R, Kennedy BE, Murphy JP, Clements D, Konda P, Giacomantonio M, Xu Z, Schlaepfer IR, Gujar S. Pathak GP, et al. Mol Ther. 2018 Aug 1;26(8):2019-2033. doi: 10.1016/j.ymthe.2018.05.026. Epub 2018 Jun 30. Mol Ther. 2018. PMID: 30078441 Free PMC article.
Reticulon-4 (RTN4), commonly known as a neurite outgrowth inhibitor (Nogo), is emerging as an important player in human cancers. ...To identify the role of RTN4 in cancer biology, we performed mass spectrometry-based quantitative proteomic analysis on …
Reticulon-4 (RTN4), commonly known as a neurite outgrowth inhibitor (Nogo), is emerging as an important player in human cancers …
RTN4 3'-UTR insertion/deletion polymorphism and susceptibility to non-small cell lung cancer in Chinese Han population.
Lu DY, Mao XH, Zhou YH, Yan XL, Wang WP, Zheng YB, Xiao JJ, Zhang P, Wang JG, Ashwani N, Ding WL, Jiang H, Shang Y, Wang MH. Lu DY, et al. Asian Pac J Cancer Prev. 2014;15(13):5249-52. doi: 10.7314/apjcp.2014.15.13.5249. Asian Pac J Cancer Prev. 2014. PMID: 25040983 Free article.
Nogo proteins play an important role in the apoptosis of cells, especially in tumor cells. RTN4 single nucleotide polymorphisms (SNPs) can influence the efficiency of transcription and translation thus being related with an individual's predisposition to cancer. The …
Nogo proteins play an important role in the apoptosis of cells, especially in tumor cells. RTN4 single nucleotide polymorphisms (SNPs …
N6-Methyladenosine-modified lncRNA LINREP promotes Glioblastoma progression by recruiting the PTBP1/HuR complex.
Ji X, Liu Z, Gao J, Bing X, He D, Liu W, Wang Y, Wei Y, Yin X, Zhang F, Han M, Lu X, Wang Z, Liu Q, Xin T. Ji X, et al. Cell Death Differ. 2023 Jan;30(1):54-68. doi: 10.1038/s41418-022-01045-5. Epub 2022 Jul 23. Cell Death Differ. 2023. PMID: 35871232 Free PMC article.
Consequently, a broad spectrum of PTBP1-induced spliced variants was generated by exon skipping, especially for the skipping of reticulon 4 (RTN4) exon 3. Interestingly, LINREP also promoted the dissociation of nuclear UPF1 from PTBP1, which increased the binding of PTBP1 …
Consequently, a broad spectrum of PTBP1-induced spliced variants was generated by exon skipping, especially for the skipping of reticulon 4 …
Knockdown of reticulon 4C by lentivirus inhibits human colorectal cancer cell growth.
Xue H, Wang Z, Chen J, Yang Z, Tang J. Xue H, et al. Mol Med Rep. 2015 Aug;12(2):2063-7. doi: 10.3892/mmr.2015.3569. Epub 2015 Mar 31. Mol Med Rep. 2015. PMID: 25847052
To investigate the biological role of RTN4-C in colorectal cancer, the expression levels of RTN4-C were initially analyzed in six colorectal cancer cell lines by reverse transcription-quantitative polymerase chain reaction and western blot analysis. .. …
To investigate the biological role of RTN4-C in colorectal cancer, the expression levels of RTN4-C were initially analy …
Cell fate regulation by reticulon-4 in human prostate cancers.
Zhao H, Su W, Zhu C, Zeng T, Yang S, Wu W, Wang D. Zhao H, et al. J Cell Physiol. 2019 Jul;234(7):10372-10385. doi: 10.1002/jcp.27704. Epub 2018 Nov 27. J Cell Physiol. 2019. PMID: 30480803
Here in our current study, we focused on its role in prostate cancer and found that RTN4 DNA copy numbers were higher in prostate cancer than normal prostate gland while its RNA and protein expressions were relatively lower. ...All these results implied that …
Here in our current study, we focused on its role in prostate cancer and found that RTN4 DNA copy numbers were higher in prost …
Novel roles of RTN4 and CLIMP-63 in regulating mitochondrial structure, bioenergetics and apoptosis.
Carter RJ, Milani M, Beckett AJ, Liu S, Prior IA, Cohen GM, Varadarajan S. Carter RJ, et al. Cell Death Dis. 2022 May 4;13(5):436. doi: 10.1038/s41419-022-04869-8. Cell Death Dis. 2022. PMID: 35508606 Free PMC article.
To investigate the complex interplay between the ER membranes and DRP1 in the context of mitochondrial structure and function, we downregulate two key ER shaping proteins, RTN4 and CLIMP-63, and demonstrate pronounced mitochondrial hyperfusion and reduced ER-mitochondria c …
To investigate the complex interplay between the ER membranes and DRP1 in the context of mitochondrial structure and function, we downregula …
SFPQ and Its Isoform as Potential Biomarker for Non-Small-Cell Lung Cancer.
Yang L, Gilbertsen A, Jacobson B, Pham J, Fujioka N, Henke CA, Kratzke RA. Yang L, et al. Int J Mol Sci. 2023 Aug 6;24(15):12500. doi: 10.3390/ijms241512500. Int J Mol Sci. 2023. PMID: 37569873 Free PMC article.
Cancer markers are measurable molecules in the blood or tissue that are produced by tumor cells or immune cells in response to cancer progression. ...Although DNA, RNA, and even physical images have been used, proteins continue to be the most common marker. There ar …
Cancer markers are measurable molecules in the blood or tissue that are produced by tumor cells or immune cells in response to can …
88 results