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Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium.
Nociari MM, Lehmann GL, Perez Bay AE, Radu RA, Jiang Z, Goicochea S, Schreiner R, Warren JD, Shan J, Adam de Beaumais S, Ménand M, Sollogoub M, Maxfield FR, Rodriguez-Boulan E. Nociari MM, et al. Among authors: radu ra. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):E1402-8. doi: 10.1073/pnas.1400530111. Epub 2014 Mar 24. Proc Natl Acad Sci U S A. 2014. PMID: 24706818 Free PMC article.
Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration.
Lenis TL, Hu J, Ng SY, Jiang Z, Sarfare S, Lloyd MB, Esposito NJ, Samuel W, Jaworski C, Bok D, Finnemann SC, Radeke MJ, Redmond TM, Travis GH, Radu RA. Lenis TL, et al. Among authors: radu ra. Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):E11120-E11127. doi: 10.1073/pnas.1802519115. Epub 2018 Nov 5. Proc Natl Acad Sci U S A. 2018. PMID: 30397118 Free PMC article.
Abnormal mTORC1 signaling leads to retinal pigment epithelium degeneration.
Huang J, Gu S, Chen M, Zhang SJ, Jiang Z, Chen X, Jiang C, Liu G, Radu RA, Sun X, Vollrath D, Du J, Yan B, Zhao C. Huang J, et al. Among authors: radu ra. Theranostics. 2019 Jan 30;9(4):1170-1180. doi: 10.7150/thno.26281. eCollection 2019. Theranostics. 2019. PMID: 30867823 Free PMC article.
73 results