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Cytokine traps: multi-component, high-affinity blockers of cytokine action.
Economides AN, Carpenter LR, Rudge JS, Wong V, Koehler-Stec EM, Hartnett C, Pyles EA, Xu X, Daly TJ, Young MR, Fandl JP, Lee F, Carver S, McNay J, Bailey K, Ramakanth S, Hutabarat R, Huang TT, Radziejewski C, Yancopoulos GD, Stahl N. Economides AN, et al. Among authors: radziejewski c. Nat Med. 2003 Jan;9(1):47-52. doi: 10.1038/nm811. Epub 2002 Dec 16. Nat Med. 2003. PMID: 12483208
VEGF-Trap: a VEGF blocker with potent antitumor effects.
Holash J, Davis S, Papadopoulos N, Croll SD, Ho L, Russell M, Boland P, Leidich R, Hylton D, Burova E, Ioffe E, Huang T, Radziejewski C, Bailey K, Fandl JP, Daly T, Wiegand SJ, Yancopoulos GD, Rudge JS. Holash J, et al. Among authors: radziejewski c. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11393-8. doi: 10.1073/pnas.172398299. Epub 2002 Aug 12. Proc Natl Acad Sci U S A. 2002. PMID: 12177445 Free PMC article.
Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering.
Davis S, Papadopoulos N, Aldrich TH, Maisonpierre PC, Huang T, Kovac L, Xu A, Leidich R, Radziejewska E, Rafique A, Goldberg J, Jain V, Bailey K, Karow M, Fandl J, Samuelsson SJ, Ioffe E, Rudge JS, Daly TJ, Radziejewski C, Yancopoulos GD. Davis S, et al. Among authors: radziejewski c. Nat Struct Biol. 2003 Jan;10(1):38-44. doi: 10.1038/nsb880. Nat Struct Biol. 2003. PMID: 12469114
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis.
Maisonpierre PC, Suri C, Jones PF, Bartunkova S, Wiegand SJ, Radziejewski C, Compton D, McClain J, Aldrich TH, Papadopoulos N, Daly TJ, Davis S, Sato TN, Yancopoulos GD. Maisonpierre PC, et al. Among authors: radziejewski c. Science. 1997 Jul 4;277(5322):55-60. doi: 10.1126/science.277.5322.55. Science. 1997. PMID: 9204896
Agrin acts via a MuSK receptor complex.
Glass DJ, Bowen DC, Stitt TN, Radziejewski C, Bruno J, Ryan TE, Gies DR, Shah S, Mattsson K, Burden SJ, DiStefano PS, Valenzuela DM, DeChiara TM, Yancopoulos GD. Glass DJ, et al. Among authors: radziejewski c. Cell. 1996 May 17;85(4):513-23. doi: 10.1016/s0092-8674(00)81252-0. Cell. 1996. PMID: 8653787 Free article.
Recombinant human and rat ciliary neurotrophic factors.
Masiakowski P, Liu HX, Radziejewski C, Lottspeich F, Oberthuer W, Wong V, Lindsay RM, Furth ME, Panayotatos N. Masiakowski P, et al. Among authors: radziejewski c. J Neurochem. 1991 Sep;57(3):1003-12. doi: 10.1111/j.1471-4159.1991.tb08250.x. J Neurochem. 1991. PMID: 1861138
38 results