Inhibition of S-adenosyl-L-methionine sterol-C-24-methyltransferase by analogues of a carbocationic ion high-energy intermediate. Structure activity relationships for C-25 heteroatoms (N, As, S) substituted triterpenoid derivatives.
Rahier A, Génot JC, Schuber F, Benveniste P, Narula AS.
Rahier A, et al.
J Biol Chem. 1984 Dec 25;259(24):15215-23.
J Biol Chem. 1984.
PMID: 6511791
Free article.
S., Rahier, A., Benveniste, P., and Schuber, F. (1981) J. Am. Chem. Soc. 103, 2408-2409). ...The positive charge leading to inhibition may be conferred by a protonated amine, a quaternary ammonium group, as well as by a sulfonium or an arsonium …
S., Rahier, A., Benveniste, P., and Schuber, F. (1981) J. Am. Chem. Soc. 103, 2408-2409). ...The positive charge leading to in …