Raikar SS - Search Results

1

PI3Kδ/γ inhibition promotes human CART cell epigenetic and metabolic reprogramming to enhance antitumor cytotoxicity.

Funk CR, Wang S, Chen KZ, Waller A, Sharma A, Edgar CL, Gupta VA, Chandrakasan S, Zoine JT, Fedanov A, Raikar SS, Koff JL, Flowers CR, Coma S, Pachter JA, Ravindranathan S, Spencer HT, Shanmugam M, Waller EK. Funk CR, et al. Among authors: raikar ss. Blood. 2022 Jan 27;139(4):523-537. doi: 10.1182/blood.2021011597. Blood. 2022. PMID: 35084470 Free PMC article.

2

Genetic engineering of chimeric antigen receptors using lamprey derived variable lymphocyte receptors.

Moot R, Raikar SS, Fleischer L, Querrey M, Tylawsky DE, Nakahara H, Doering CB, Spencer HT. Moot R, et al. Among authors: raikar ss. Mol Ther Oncolytics. 2016 Dec 7;3:16026. doi: 10.1038/mto.2016.26. eCollection 2016. Mol Ther Oncolytics. 2016. PMID: 27933313 Free PMC article.

3

Isolated myeloperoxidase expression in pediatric B/myeloid mixed phenotype acute leukemia is linked with better survival.

Raikar SS, Park SI, Leong T, Jaye DL, Keller FG, Horan JT, Woods WG. Raikar SS, et al. Blood. 2018 Feb 1;131(5):573-577. doi: 10.1182/blood-2017-09-807602. Epub 2017 Dec 9. Blood. 2018. PMID: 29223952 Free article. No abstract available.

4

Improving T-cell expansion and function for adoptive T-cell therapy using ex vivo treatment with PI3Kδ inhibitors and VIP antagonists.

Petersen CT, Hassan M, Morris AB, Jeffery J, Lee K, Jagirdar N, Staton AD, Raikar SS, Spencer HT, Sulchek T, Flowers CR, Waller EK. Petersen CT, et al. Among authors: raikar ss. Blood Adv. 2018 Feb 13;2(3):210-223. doi: 10.1182/bloodadvances.2017011254. Blood Adv. 2018. PMID: 29386194 Free PMC article.

5

Development of chimeric antigen receptors targeting T-cell malignancies using two structurally different anti-CD5 antigen binding domains in NK and CRISPR-edited T cell lines.

Raikar SS, Fleischer LC, Moot R, Fedanov A, Paik NY, Knight KA, Doering CB, Spencer HT. Raikar SS, et al. Oncoimmunology. 2017 Dec 26;7(3):e1407898. doi: 10.1080/2162402X.2017.1407898. eCollection 2018. Oncoimmunology. 2017. PMID: 29399409 Free PMC article.

6

Targeting T cell malignancies using CAR-based immunotherapy: challenges and potential solutions.

Fleischer LC, Spencer HT, Raikar SS. Fleischer LC, et al. Among authors: raikar ss. J Hematol Oncol. 2019 Dec 29;12(1):141. doi: 10.1186/s13045-019-0801-y. J Hematol Oncol. 2019. PMID: 31884955 Free PMC article. Review.

7

Bortezomib enhances cytotoxicity of ex vivo-expanded gamma delta T cells against acute myeloid leukemia and T-cell acute lymphoblastic leukemia.

Story JY, Zoine JT, Burnham RE, Hamilton JAG, Spencer HT, Doering CB, Raikar SS. Story JY, et al. Among authors: raikar ss. Cytotherapy. 2021 Jan;23(1):12-24. doi: 10.1016/j.jcyt.2020.09.010. Epub 2020 Nov 6. Cytotherapy. 2021. PMID: 33168453 Free PMC article.

8

Hurdles Associated with the Translational Use of Genetically Modified Cells.

Raikar SS, Spencer HT. Raikar SS, et al. Curr Stem Cell Rep. 2018 Mar;4(1):39-45. doi: 10.1007/s40778-018-0115-y. Epub 2018 Feb 17. Curr Stem Cell Rep. 2018. PMID: 33381387 Free PMC article.

9

Interleukin-37 improves T-cell-mediated immunity and chimeric antigen receptor T-cell therapy in aged backgrounds.

Hamilton JAG, Lee MY, Hunter R, Ank RS, Story JY, Talekar G, Sisroe T, Ballak DB, Fedanov A, Porter CC, Eisenmesser EZ, Dinarello CA, Raikar SS, DeGregori J, Henry CJ. Hamilton JAG, et al. Among authors: raikar ss. Aging Cell. 2021 Feb;20(2):e13309. doi: 10.1111/acel.13309. Epub 2021 Jan 22. Aging Cell. 2021. PMID: 33480151 Free PMC article.

10

Enhancing the effectiveness of γδ T cells by mRNA transfection of chimeric antigen receptors or bispecific T cell engagers.

Becker SA, Petrich BG, Yu B, Knight KA, Brown HC, Raikar SS, Doering CB, Spencer HT. Becker SA, et al. Among authors: raikar ss. Mol Ther Oncolytics. 2023 May 22;29:145-157. doi: 10.1016/j.omto.2023.05.007. eCollection 2023 Jun 15. Mol Ther Oncolytics. 2023. PMID: 37387794 Free PMC article.

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