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Δ8-Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB2 receptors.
Bátkai S, Mukhopadhyay P, Horváth B, Rajesh M, Gao RY, Mahadevan A, Amere M, Battista N, Lichtman AH, Gauson LA, Maccarrone M, Pertwee RG, Pacher P. Bátkai S, et al. Among authors: rajesh m. Br J Pharmacol. 2012 Apr;165(8):2450-61. doi: 10.1111/j.1476-5381.2011.01410.x. Br J Pharmacol. 2012. PMID: 21470208 Free PMC article.
Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death.
Mukhopadhyay P, Rajesh M, Horváth B, Bátkai S, Park O, Tanchian G, Gao RY, Patel V, Wink DA, Liaudet L, Haskó G, Mechoulam R, Pacher P. Mukhopadhyay P, et al. Among authors: rajesh m. Free Radic Biol Med. 2011 May 15;50(10):1368-81. doi: 10.1016/j.freeradbiomed.2011.02.021. Epub 2011 Mar 11. Free Radic Biol Med. 2011. PMID: 21362471 Free PMC article.
A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury.
Horváth B, Magid L, Mukhopadhyay P, Bátkai S, Rajesh M, Park O, Tanchian G, Gao RY, Goodfellow CE, Glass M, Mechoulam R, Pacher P. Horváth B, et al. Among authors: rajesh m. Br J Pharmacol. 2012 Apr;165(8):2462-78. doi: 10.1111/j.1476-5381.2011.01381.x. Br J Pharmacol. 2012. PMID: 21449982 Free PMC article.
Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury.
Bátkai S, Osei-Hyiaman D, Pan H, El-Assal O, Rajesh M, Mukhopadhyay P, Hong F, Harvey-White J, Jafri A, Haskó G, Huffman JW, Gao B, Kunos G, Pacher P. Bátkai S, et al. Among authors: rajesh m. FASEB J. 2007 Jun;21(8):1788-800. doi: 10.1096/fj.06-7451com. Epub 2007 Feb 27. FASEB J. 2007. PMID: 17327359 Free PMC article.
CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion.
Rajesh M, Mukhopadhyay P, Bátkai S, Haskó G, Liaudet L, Huffman JW, Csiszar A, Ungvari Z, Mackie K, Chatterjee S, Pacher P. Rajesh M, et al. Am J Physiol Heart Circ Physiol. 2007 Oct;293(4):H2210-8. doi: 10.1152/ajpheart.00688.2007. Epub 2007 Jul 27. Am J Physiol Heart Circ Physiol. 2007. PMID: 17660390 Free PMC article.
210 results