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Remethylation of Dnmt3a-/- hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing.
Ketkar S, Verdoni AM, Smith AM, Bangert CV, Leight ER, Chen DY, Brune MK, Helton NM, Hoock M, George DR, Fronick C, Fulton RS, Ramakrishnan SM, Chang GS, Petti AA, Spencer DH, Miller CA, Ley TJ. Ketkar S, et al. Among authors: ramakrishnan sm. Proc Natl Acad Sci U S A. 2020 Feb 11;117(6):3123-3134. doi: 10.1073/pnas.1918611117. Epub 2020 Jan 29. Proc Natl Acad Sci U S A. 2020. PMID: 31996479 Free PMC article.
Tumor suppressor function of Gata2 in acute promyelocytic leukemia.
Katerndahl CDS, Rogers ORS, Day RB, Cai MA, Rooney TP, Helton NM, Hoock M, Ramakrishnan SM, Nonavinkere Srivatsan S, Wartman LD, Miller CA, Ley TJ. Katerndahl CDS, et al. Among authors: ramakrishnan sm. Blood. 2021 Sep 30;138(13):1148-1161. doi: 10.1182/blood.2021011758. Blood. 2021. PMID: 34125173 Free PMC article.
Functional and epigenetic phenotypes of humans and mice with DNMT3A Overgrowth Syndrome.
Smith AM, LaValle TA, Shinawi M, Ramakrishnan SM, Abel HJ, Hill CA, Kirkland NM, Rettig MP, Helton NM, Heath SE, Ferraro F, Chen DY, Adak S, Semenkovich CF, Christian DL, Martin JR, Gabel HW, Miller CA, Ley TJ. Smith AM, et al. Among authors: ramakrishnan sm. Nat Commun. 2021 Jul 27;12(1):4549. doi: 10.1038/s41467-021-24800-7. Nat Commun. 2021. PMID: 34315901 Free PMC article.
Tumor suppressor function of WT1 in acute promyelocytic leukemia.
Christopher MJ, Katerndahl CDS, LeBlanc HR, Elmendorf TT, Basu V, Gang M, Menssen AJ, Spencer DH, Duncavage EJ, Ketkar S, Wartman LD, Ramakrishnan SM, Miller CA, Ley TJ. Christopher MJ, et al. Among authors: ramakrishnan sm. Haematologica. 2022 Jan 1;107(1):342-346. doi: 10.3324/haematol.2021.279601. Haematologica. 2022. PMID: 34670359 Free PMC article. No abstract available.
Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes.
Ferraro F, Miller CA, Christensen KA, Helton NM, O'Laughlin M, Fronick CC, Fulton RS, Kohlschmidt J, Eisfeld AK, Bloomfield CD, Ramakrishnan SM, Day RB, Wartman LD, Uy GL, Welch JS, Christopher MJ, Heath SE, Baty JD, Schuelke MJ, Payton JE, Spencer DH, Rettig MP, Link DC, Walter MJ, Westervelt P, DiPersio JF, Ley TJ. Ferraro F, et al. Among authors: ramakrishnan sm. Proc Natl Acad Sci U S A. 2021 Dec 7;118(49):e2116427118. doi: 10.1073/pnas.2116427118. Proc Natl Acad Sci U S A. 2021. PMID: 34845035 Free PMC article.
Genetic and Transcriptional Contributions to Relapse in Normal Karyotype Acute Myeloid Leukemia.
Petti AA, Khan SM, Xu Z, Helton N, Fronick CC, Fulton R, Ramakrishnan SM, Nonavinkere Srivatsan S, Heath SE, Westervelt P, Payton JE, Walter MJ, Link DC, DiPersio J, Miller C, Ley TJ. Petti AA, et al. Among authors: ramakrishnan sm. Blood Cancer Discov. 2022 Jan;3(1):32-49. doi: 10.1158/2643-3230.BCD-21-0050. Epub 2021 Aug 24. Blood Cancer Discov. 2022. PMID: 35019859 Free PMC article.
Proteomic and phosphoproteomic landscapes of acute myeloid leukemia.
Kramer MH, Zhang Q, Sprung R, Day RB, Erdmann-Gilmore P, Li Y, Xu Z, Helton NM, George DR, Mi Y, Westervelt P, Payton JE, Ramakrishnan SM, Miller CA, Link DC, DiPersio JF, Walter MJ, Townsend RR, Ley TJ. Kramer MH, et al. Among authors: ramakrishnan sm. Blood. 2022 Sep 29;140(13):1533-1548. doi: 10.1182/blood.2022016033. Blood. 2022. PMID: 35895896 Free PMC article.
25 results