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HES5 silencing is an early and recurrent change in prostate tumourigenesis.
Massie CE, Spiteri I, Ross-Adams H, Luxton H, Kay J, Whitaker HC, Dunning MJ, Lamb AD, Ramos-Montoya A, Brewer DS, Cooper CS, Eeles R; UK Prostate ICGC Group; Warren AY, Tavaré S, Neal DE, Lynch AG. Massie CE, et al. Endocr Relat Cancer. 2015 Apr;22(2):131-44. doi: 10.1530/ERC-14-0454. Epub 2015 Jan 5. Endocr Relat Cancer. 2015. PMID: 25560400 Free PMC article.
Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study.
Ross-Adams H, Lamb AD, Dunning MJ, Halim S, Lindberg J, Massie CM, Egevad LA, Russell R, Ramos-Montoya A, Vowler SL, Sharma NL, Kay J, Whitaker H, Clark J, Hurst R, Gnanapragasam VJ, Shah NC, Warren AY, Cooper CS, Lynch AG, Stark R, Mills IG, Grönberg H, Neal DE; CamCaP Study Group. Ross-Adams H, et al. EBioMedicine. 2015 Jul 29;2(9):1133-44. doi: 10.1016/j.ebiom.2015.07.017. eCollection 2015 Sep. EBioMedicine. 2015. PMID: 26501111 Free PMC article.
The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis.
Massie CE, Lynch A, Ramos-Montoya A, Boren J, Stark R, Fazli L, Warren A, Scott H, Madhu B, Sharma N, Bon H, Zecchini V, Smith DM, Denicola GM, Mathews N, Osborne M, Hadfield J, Macarthur S, Adryan B, Lyons SK, Brindle KM, Griffiths J, Gleave ME, Rennie PS, Neal DE, Mills IG. Massie CE, et al. EMBO J. 2011 May 20;30(13):2719-33. doi: 10.1038/emboj.2011.158. EMBO J. 2011. PMID: 21602788 Free PMC article.
HES6 drives a critical AR transcriptional programme to induce castration-resistant prostate cancer through activation of an E2F1-mediated cell cycle network.
Ramos-Montoya A, Lamb AD, Russell R, Carroll T, Jurmeister S, Galeano-Dalmau N, Massie CE, Boren J, Bon H, Theodorou V, Vias M, Shaw GL, Sharma NL, Ross-Adams H, Scott HE, Vowler SL, Howat WJ, Warren AY, Wooster RF, Mills IG, Neal DE. Ramos-Montoya A, et al. EMBO Mol Med. 2014 May;6(5):651-61. doi: 10.1002/emmm.201303581. EMBO Mol Med. 2014. PMID: 24737870 Free PMC article.
The Early Effects of Rapid Androgen Deprivation on Human Prostate Cancer.
Shaw GL, Whitaker H, Corcoran M, Dunning MJ, Luxton H, Kay J, Massie CE, Miller JL, Lamb AD, Ross-Adams H, Russell R, Nelson AW, Eldridge MD, Lynch AG, Ramos-Montoya A, Mills IG, Taylor AE, Arlt W, Shah N, Warren AY, Neal DE. Shaw GL, et al. Eur Urol. 2016 Aug;70(2):214-8. doi: 10.1016/j.eururo.2015.10.042. Epub 2015 Nov 10. Eur Urol. 2016. PMID: 26572708 Free PMC article. Clinical Trial.
HNF1B variants associate with promoter methylation and regulate gene networks activated in prostate and ovarian cancer.
Ross-Adams H, Ball S, Lawrenson K, Halim S, Russell R, Wells C, Strand SH, Ørntoft TF, Larson M, Armasu S, Massie CE, Asim M, Mortensen MM, Borre M, Woodfine K, Warren AY, Lamb AD, Kay J, Whitaker H, Ramos-Montoya A, Murrell A, Sørensen KD, Fridley BL, Goode EL, Gayther SA, Masters J, Neal DE, Mills IG. Ross-Adams H, et al. Oncotarget. 2016 Nov 15;7(46):74734-74746. doi: 10.18632/oncotarget.12543. Oncotarget. 2016. PMID: 27732966 Free PMC article.
Independence of HIF1a and androgen signaling pathways in prostate cancer.
Tran MGB, Bibby BAS, Yang L, Lo F, Warren AY, Shukla D, Osborne M, Hadfield J, Carroll T, Stark R, Scott H, Ramos-Montoya A, Massie C, Maxwell P, West CML, Mills IG, Neal DE. Tran MGB, et al. Among authors: ramos montoya a. BMC Cancer. 2020 May 25;20(1):469. doi: 10.1186/s12885-020-06890-6. BMC Cancer. 2020. PMID: 32450824 Free PMC article.
39 results