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Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma.
Mai WX, Gosa L, Daniels VW, Ta L, Tsang JE, Higgins B, Gilmore WB, Bayley NA, Harati MD, Lee JT, Yong WH, Kornblum HI, Bensinger SJ, Mischel PS, Rao PN, Clark PM, Cloughesy TF, Letai A, Nathanson DA. Mai WX, et al. Among authors: rao pn. Nat Med. 2017 Nov;23(11):1342-1351. doi: 10.1038/nm.4418. Epub 2017 Oct 9. Nat Med. 2017. PMID: 29035366 Free PMC article.
Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA.
Nathanson DA, Gini B, Mottahedeh J, Visnyei K, Koga T, Gomez G, Eskin A, Hwang K, Wang J, Masui K, Paucar A, Yang H, Ohashi M, Zhu S, Wykosky J, Reed R, Nelson SF, Cloughesy TF, James CD, Rao PN, Kornblum HI, Heath JR, Cavenee WK, Furnari FB, Mischel PS. Nathanson DA, et al. Among authors: rao pn. Science. 2014 Jan 3;343(6166):72-6. doi: 10.1126/science.1241328. Epub 2013 Dec 5. Science. 2014. PMID: 24310612 Free PMC article.
Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity.
Turner KM, Deshpande V, Beyter D, Koga T, Rusert J, Lee C, Li B, Arden K, Ren B, Nathanson DA, Kornblum HI, Taylor MD, Kaushal S, Cavenee WK, Wechsler-Reya R, Furnari FB, Vandenberg SR, Rao PN, Wahl GM, Bafna V, Mischel PS. Turner KM, et al. Among authors: rao pn. Nature. 2017 Mar 2;543(7643):122-125. doi: 10.1038/nature21356. Epub 2017 Feb 8. Nature. 2017. PMID: 28178237 Free PMC article.
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.
Mellinghoff IK, Wang MY, Vivanco I, Haas-Kogan DA, Zhu S, Dia EQ, Lu KV, Yoshimoto K, Huang JH, Chute DJ, Riggs BL, Horvath S, Liau LM, Cavenee WK, Rao PN, Beroukhim R, Peck TC, Lee JC, Sellers WR, Stokoe D, Prados M, Cloughesy TF, Sawyers CL, Mischel PS. Mellinghoff IK, et al. Among authors: rao pn. N Engl J Med. 2005 Nov 10;353(19):2012-24. doi: 10.1056/NEJMoa051918. N Engl J Med. 2005. PMID: 16282176 Free article.
Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain.
Lee JC, Vivanco I, Beroukhim R, Huang JH, Feng WL, DeBiasi RM, Yoshimoto K, King JC, Nghiemphu P, Yuza Y, Xu Q, Greulich H, Thomas RK, Paez JG, Peck TC, Linhart DJ, Glatt KA, Getz G, Onofrio R, Ziaugra L, Levine RL, Gabriel S, Kawaguchi T, O'Neill K, Khan H, Liau LM, Nelson SF, Rao PN, Mischel P, Pieper RO, Cloughesy T, Leahy DJ, Sellers WR, Sawyers CL, Meyerson M, Mellinghoff IK. Lee JC, et al. Among authors: rao pn. PLoS Med. 2006 Dec;3(12):e485. doi: 10.1371/journal.pmed.0030485. PLoS Med. 2006. PMID: 17177598 Free PMC article.
Src as a novel therapeutic target for endometriosis.
Lawrenson K, Lee N, Torres HA, Lee JM, Brueggmann D, Rao PN, Noushmehr H, Gayther SA. Lawrenson K, et al. Among authors: rao pn. Gynecol Oncol. 2014 Oct;135(1):100-7. doi: 10.1016/j.ygyno.2014.06.016. Epub 2014 Jun 24. Gynecol Oncol. 2014. PMID: 24972189
Solid tumor cytogenetics: current perspectives.
Nanjangud G, Amarillo I, Rao PN. Nanjangud G, et al. Among authors: rao pn. Clin Lab Med. 2011 Dec;31(4):785-811, xi. doi: 10.1016/j.cll.2011.07.007. Epub 2011 Oct 21. Clin Lab Med. 2011. PMID: 22118748 Review.
Pericytic mimicry in well-differentiated liposarcoma/atypical lipomatous tumor.
Shen J, Shrestha S, Rao PN, Asatrian G, Scott MA, Nguyen V, Giacomelli P, Soo C, Ting K, Eilber FC, Peault B, Dry SM, James AW. Shen J, et al. Among authors: rao pn. Hum Pathol. 2016 Aug;54:92-9. doi: 10.1016/j.humpath.2016.03.008. Epub 2016 Apr 8. Hum Pathol. 2016. PMID: 27063472 Free PMC article.
652 results