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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1982 2
1985 3
1986 1
1987 3
1989 4
1990 1
1991 4
1992 1
1993 5
1994 1
1995 4
1996 1
1997 1
1998 1
1999 3
2000 3
2001 4
2002 4
2003 8
2004 5
2005 11
2006 9
2007 9
2008 20
2009 16
2010 19
2011 29
2012 17
2013 28
2014 28
2015 24
2016 23
2017 15
2018 19
2019 22
2020 18
2021 25
2022 27
2023 29
2024 6

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408 results

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Page 1
Epigenetic regulation in human melanoma: past and future.
Sarkar D, Leung EY, Baguley BC, Finlay GJ, Askarian-Amiri ME. Sarkar D, et al. Epigenetics. 2015;10(2):103-21. doi: 10.1080/15592294.2014.1003746. Epigenetics. 2015. PMID: 25587943 Free PMC article. Review.
Recurrent RARB Translocations in Acute Promyelocytic Leukemia Lacking RARA Translocation.
Osumi T, Tsujimoto SI, Tamura M, Uchiyama M, Nakabayashi K, Okamura K, Yoshida M, Tomizawa D, Watanabe A, Takahashi H, Hori T, Yamamoto S, Hamamoto K, Migita M, Ogata-Kawata H, Uchiyama T, Kizawa H, Ueno-Yokohata H, Shirai R, Seki M, Ohki K, Takita J, Inukai T, Ogawa S, Kitamura T, Matsumoto K, Hata K, Kiyokawa N, Goyama S, Kato M. Osumi T, et al. Cancer Res. 2018 Aug 15;78(16):4452-4458. doi: 10.1158/0008-5472.CAN-18-0840. Epub 2018 Jun 19. Cancer Res. 2018. PMID: 29921692
Four of five RARA-negative APL cases had translocations involving retinoic acid receptor-beta (RARB) translocations, and TBL1XR1-RARB was identified as an in-frame fusion in three cases; one case had an RARB rearrangement detected by FISH, although the partne …
Four of five RARA-negative APL cases had translocations involving retinoic acid receptor-beta (RARB) translocations, and TBL1XR1-R …
Epigenetic regulation of RARB overcomes the radio-resistance of colorectal carcinoma cells via cancer stem cells.
Shu Y, Lan J, Hu Z, Liu W, Song R. Shu Y, et al. J Radiat Res. 2023 Jan 20;64(1):11-23. doi: 10.1093/jrr/rrac060. J Radiat Res. 2023. PMID: 36214504 Free PMC article.
Also, RARB was poorly expressed in our isolated CSCs, and overexpression of RARB inhibited the properties of CSCs and enhanced radiotherapy sensitivity. ...DNA methyltransferases (DNMT1) was found to be recruited into the RARB promoter. 5-AzaC treatment inhib …
Also, RARB was poorly expressed in our isolated CSCs, and overexpression of RARB inhibited the properties of CSCs and enhanced …
Regulation of prefrontal patterning and connectivity by retinoic acid.
Shibata M, Pattabiraman K, Lorente-Galdos B, Andrijevic D, Kim SK, Kaur N, Muchnik SK, Xing X, Santpere G, Sousa AMM, Sestan N. Shibata M, et al. Nature. 2021 Oct;598(7881):483-488. doi: 10.1038/s41586-021-03953-x. Epub 2021 Oct 1. Nature. 2021. PMID: 34599305 Free PMC article.
Genetic deletions in mice revealed that retinoic acid signalling through the retinoic acid receptors RXRG and RARB, as well as CYP26B1-dependent catabolism, are involved in proper molecular patterning of prefrontal and motor areas, development of PFC-mediodorsal thalamus c …
Genetic deletions in mice revealed that retinoic acid signalling through the retinoic acid receptors RXRG and RARB, as well as CYP26B …
Clinical and genomic characterization of an ATRA-insensitive acute promyelocytic leukemia variant with a FNDC3B::RARB fusion.
Kirkham JK, Liu YC, Foy SG, Ma J, Gheorghe G, Furtado LV, Popescu MI, Klco JM, Karol SE, Blackburn PR. Kirkham JK, et al. Genes Chromosomes Cancer. 2023 Oct;62(10):617-623. doi: 10.1002/gcc.23180. Epub 2023 Jun 7. Genes Chromosomes Cancer. 2023. PMID: 37283355
We present a 13-year-old male diagnosed with variant APL with a novel FNDC3B::RARB in-frame fusion that showed no response to ATRA but responded well to conventional AML therapy. While FNDC3B has been identified as a rare RARA translocation partner in ATRA-sensitive varian …
We present a 13-year-old male diagnosed with variant APL with a novel FNDC3B::RARB in-frame fusion that showed no response to ATRA bu …
Ophthalmic manifestations associated with RARB mutations.
Wangtiraumnuay N, Kopinsky S, Iyer P, Capasso J, Whitehead R, Schneider A, Levin AV. Wangtiraumnuay N, et al. Clin Dysmorphol. 2019 Jan;28(1):46-49. doi: 10.1097/MCD.0000000000000246. Clin Dysmorphol. 2019. PMID: 30281527 No abstract available.
Transgene integration causes RARB downregulation in homozygous Tg4-42 mice.
Hinteregger B, Loeffler T, Flunkert S, Neddens J, Birner-Gruenberger R, Bayer TA, Madl T, Hutter-Paier B. Hinteregger B, et al. Sci Rep. 2020 Apr 14;10(1):6377. doi: 10.1038/s41598-020-63512-8. Sci Rep. 2020. PMID: 32286473 Free PMC article.
These findings were also confirmed on protein level with highly decreased retinoic acid receptor beta protein levels in homozygous Tg4-42 mice and may have an impact on the previously described phenotype of homozygous Tg4-42 mice to be solely dependent on amyloid-ss 4-42 expressi …
These findings were also confirmed on protein level with highly decreased retinoic acid receptor beta protein levels in homozygous Tg4-42 mi …
Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity.
Schönberger K, Obier N, Romero-Mulero MC, Cauchy P, Mess J, Pavlovich PV, Zhang YW, Mitterer M, Rettkowski J, Lalioti ME, Jäcklein K, Curtis JD, Féret B, Sommerkamp P, Morganti C, Ito K, Ghyselinck NB, Trompouki E, Buescher JM, Pearce EL, Cabezas-Wallscheid N. Schönberger K, et al. Cell Stem Cell. 2022 Jan 6;29(1):131-148.e10. doi: 10.1016/j.stem.2021.10.002. Epub 2021 Oct 26. Cell Stem Cell. 2022. PMID: 34706256 Free PMC article.
In contrast to the traditional view, we demonstrate that Cyp26b1 is indispensable for production of the active metabolite 4-oxo-RA. Further, RA receptor beta (Rarb) is required for complete transmission of 4-oxo-RA-mediated signaling to maintain stem cells. ...
In contrast to the traditional view, we demonstrate that Cyp26b1 is indispensable for production of the active metabolite 4-oxo-RA. Further, …
Promoter hypermethylation of RARB and GSTP1 genes in plasma cell-free DNA as breast cancer biomarkers in Peruvian women.
Danos P, Giannoni-Luza S, Murillo Carrasco AG, Acosta O, Guevara-Fujita ML, Cotrina Concha JM, Guerra Miller H, Pinto Oblitas J, Aguilar Cartagena A, Araujo JM, Fujita R, Buleje Sono JL. Danos P, et al. Mol Genet Genomic Med. 2023 Dec;11(12):e2260. doi: 10.1002/mgg3.2260. Epub 2023 Aug 7. Mol Genet Genomic Med. 2023. PMID: 37548362 Free PMC article.
RESULTS: A significant association was not found between breast cancer and the RARB PMR (OR = 1.90; 95% CI [0.62-6.18]; p = 0.210) or the GSTP1 PMR (OR = 6.57; 95% CI [0.75-307.66]; p = 0.114). ...The methylated promoter of the RARB + GSTP1 genes needs further valid …
RESULTS: A significant association was not found between breast cancer and the RARB PMR (OR = 1.90; 95% CI [0.62-6.18]; p = 0.210) or …
408 results