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A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.
Begley DW, Fox D 3rd, Jenner D, Juli C, Pierce PG, Abendroth J, Muruthi M, Safford K, Anderson V, Atkins K, Barnes SR, Moen SO, Raymond AC, Stacy R, Myler PJ, Staker BL, Harmer NJ, Norville IH, Holzgrabe U, Sarkar-Tyson M, Edwards TE, Lorimer DD. Begley DW, et al. Among authors: raymond ac. Antimicrob Agents Chemother. 2014;58(3):1458-67. doi: 10.1128/AAC.01875-13. Epub 2013 Dec 23. Antimicrob Agents Chemother. 2014. PMID: 24366729 Free PMC article.
Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1.
Moen SO, Abendroth J, Fairman JW, Baydo RO, Bullen J, Kirkwood JL, Barnes SR, Raymond AC, Begley DW, Henkel G, McCormack K, Tam VC, Phan I, Staker BL, Stacy R, Myler PJ, Lorimer D, Edwards TE. Moen SO, et al. Among authors: raymond ac. Sci Rep. 2014 Aug 4;4:5944. doi: 10.1038/srep05944. Sci Rep. 2014. PMID: 25089892 Free PMC article.
High-resolution Crystal Structure of Dimeric VP40 From Sudan ebolavirus.
Clifton MC, Bruhn JF, Atkins K, Webb TL, Baydo RO, Raymond A, Lorimer DD, Edwards TE, Myler PJ, Saphire EO. Clifton MC, et al. J Infect Dis. 2015 Oct 1;212 Suppl 2(Suppl 2):S167-71. doi: 10.1093/infdis/jiv090. Epub 2015 May 9. J Infect Dis. 2015. PMID: 25957961 Free PMC article.
Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis.
Begley DW, Edwards TE, Raymond AC, Smith ER, Hartley RC, Abendroth J, Sankaran B, Lorimer DD, Myler PJ, Staker BL, Stewart LJ. Begley DW, et al. Among authors: raymond ac. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Sep 1;67(Pt 9):1070-7. doi: 10.1107/S1744309111029009. Epub 2011 Aug 16. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21904052 Free PMC article.
Gene Composer in a structural genomics environment.
Lorimer D, Raymond A, Mixon M, Burgin A, Staker B, Stewart L. Lorimer D, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Sep 1;67(Pt 9):985-91. doi: 10.1107/S1744309111027424. Epub 2011 Aug 13. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21904038 Free PMC article.
Structure of the Reston ebolavirus VP30 C-terminal domain.
Clifton MC, Kirchdoerfer RN, Atkins K, Abendroth J, Raymond A, Grice R, Barnes S, Moen S, Lorimer D, Edwards TE, Myler PJ, Saphire EO. Clifton MC, et al. Acta Crystallogr F Struct Biol Commun. 2014 Apr;70(Pt 4):457-60. doi: 10.1107/S2053230X14003811. Epub 2014 Mar 25. Acta Crystallogr F Struct Biol Commun. 2014. PMID: 24699737 Free PMC article.
The Protein Maker: an automated system for high-throughput parallel purification.
Smith ER, Begley DW, Anderson V, Raymond AC, Haffner TE, Robinson JI, Edwards TE, Duncan N, Gerdts CJ, Mixon MB, Nollert P, Staker BL, Stewart LJ. Smith ER, et al. Among authors: raymond ac. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Sep 1;67(Pt 9):1015-21. doi: 10.1107/S1744309111028776. Epub 2011 Aug 13. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21904043 Free PMC article.
Biological and structural characterization of a host-adapting amino acid in influenza virus.
Yamada S, Hatta M, Staker BL, Watanabe S, Imai M, Shinya K, Sakai-Tagawa Y, Ito M, Ozawa M, Watanabe T, Sakabe S, Li C, Kim JH, Myler PJ, Phan I, Raymond A, Smith E, Stacy R, Nidom CA, Lank SM, Wiseman RW, Bimber BN, O'Connor DH, Neumann G, Stewart LJ, Kawaoka Y. Yamada S, et al. PLoS Pathog. 2010 Aug 5;6(8):e1001034. doi: 10.1371/journal.ppat.1001034. PLoS Pathog. 2010. PMID: 20700447 Free PMC article.
33 results