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scRNA-seq of human vitiligo reveals complex networks of subclinical immune activation and a role for CCR5 in Treg function.
Gellatly KJ, Strassner JP, Essien K, Refat MA, Murphy RL, Coffin-Schmitt A, Pandya AG, Tovar-Garza A, Frisoli ML, Fan X, Ding X, Kim EE, Abbas Z, McDonel P, Garber M, Harris JE. Gellatly KJ, et al. Among authors: refat ma. Sci Transl Med. 2021 Sep 8;13(610):eabd8995. doi: 10.1126/scitranslmed.abd8995. Epub 2021 Sep 8. Sci Transl Med. 2021. PMID: 34516831 Free PMC article.
Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo.
Richmond JM, Strassner JP, Zapata L Jr, Garg M, Riding RL, Refat MA, Fan X, Azzolino V, Tovar-Garza A, Tsurushita N, Pandya AG, Tso JY, Harris JE. Richmond JM, et al. Among authors: refat ma. Sci Transl Med. 2018 Jul 18;10(450):eaam7710. doi: 10.1126/scitranslmed.aam7710. Sci Transl Med. 2018. PMID: 30021889 Free PMC article.
Systemic therapies in vitiligo: a review.
Fatima S, Abbas T, Refat MA, Harris JE, Lim HW, Hamzavi IH, Mohammad TF. Fatima S, et al. Among authors: refat ma. Int J Dermatol. 2023 Mar;62(3):279-289. doi: 10.1111/ijd.16114. Epub 2022 Feb 7. Int J Dermatol. 2023. PMID: 35133006 Review.
CXCL9 Links Skin Inflammation and Fibrosis through CXCR3-Dependent Upregulation of Col1a1 in Fibroblasts.
Richmond JM, Patel D, Watanabe T, Chen HW, Martyanov V, Werner G, Garg M, Haddadi NS, Refat MA, Mahmoud BH, Wong LD, Dresser K, Deng A, Zhu JL, McAlpine W, Hosler GA, Feghali-Bostwick CA, Whitfield ML, Harris JE, Torok KS, Jacobe HT. Richmond JM, et al. Among authors: refat ma. J Invest Dermatol. 2023 Jul;143(7):1138-1146.e12. doi: 10.1016/j.jid.2022.11.025. Epub 2023 Jan 25. J Invest Dermatol. 2023. PMID: 36708947
Spatial characterization of interface dermatitis in cutaneous lupus reveals novel chemokine ligand-receptor pairs that drive disease.
Shakiba S, Haddadi NS, Afshari K, Lubov JE, Raef HS, Li R, Yildiz-Altay Ü, Daga M, Refat MA, Kim E, de Laflin JG, Akabane A, Sherman S, MacDonald E, Strassner JP, Zhang L, Leon M, Baer CE, Dresser K, Liang Y, Whitley JB, Skopelja-Gardner S, Harris JE, Deng A, Vesely MD, Rashighi M, Richmond J. Shakiba S, et al. Among authors: refat ma. bioRxiv [Preprint]. 2024 Jan 6:2024.01.05.574422. doi: 10.1101/2024.01.05.574422. bioRxiv. 2024. PMID: 38260617 Free PMC article. Preprint.
Current Insights in Cutaneous Lupus Erythematosus Immunopathogenesis.
Garelli CJ, Refat MA, Nanaware PP, Ramirez-Ortiz ZG, Rashighi M, Richmond JM. Garelli CJ, et al. Among authors: refat ma. Front Immunol. 2020 Jul 2;11:1353. doi: 10.3389/fimmu.2020.01353. eCollection 2020. Front Immunol. 2020. PMID: 32714331 Free PMC article. Review.