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Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance.
Sørensen AL, Reis CA, Tarp MA, Mandel U, Ramachandran K, Sankaranarayanan V, Schwientek T, Graham R, Taylor-Papadimitriou J, Hollingsworth MA, Burchell J, Clausen H. Sørensen AL, et al. Among authors: reis ca. Glycobiology. 2006 Feb;16(2):96-107. doi: 10.1093/glycob/cwj044. Epub 2005 Oct 5. Glycobiology. 2006. PMID: 16207894
Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer.
Burford B, Gentry-Maharaj A, Graham R, Allen D, Pedersen JW, Nudelman AS, Blixt O, Fourkala EO, Bueti D, Dawnay A, Ford J, Desai R, David L, Trinder P, Acres B, Schwientek T, Gammerman A, Reis CA, Silva L, Osório H, Hallett R, Wandall HH, Mandel U, Hollingsworth MA, Jacobs I, Fentiman I, Clausen H, Taylor-Papadimitriou J, Menon U, Burchell JM. Burford B, et al. Among authors: reis ca. Br J Cancer. 2013 May 28;108(10):2045-55. doi: 10.1038/bjc.2013.214. Epub 2013 May 7. Br J Cancer. 2013. PMID: 23652307 Free PMC article.
ST6GalNAc-I controls expression of sialyl-Tn antigen in gastrointestinal tissues.
Marcos NT, Bennett EP, Gomes J, Magalhaes A, Gomes C, David L, Dar I, Jeanneau C, DeFrees S, Krustrup D, Vogel LK, Kure EH, Burchell J, Taylor-Papadimitriou J, Clausen H, Mandel U, Reis CA. Marcos NT, et al. Among authors: reis ca. Front Biosci (Elite Ed). 2011 Jun 1;3(4):1443-55. doi: 10.2741/e345. Front Biosci (Elite Ed). 2011. PMID: 21622148 Free article.
Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila.
Schwientek T, Bennett EP, Flores C, Thacker J, Hollmann M, Reis CA, Behrens J, Mandel U, Keck B, Schäfer MA, Haselmann K, Zubarev R, Roepstorff P, Burchell JM, Taylor-Papadimitriou J, Hollingsworth MA, Clausen H. Schwientek T, et al. Among authors: reis ca. J Biol Chem. 2002 Jun 21;277(25):22623-38. doi: 10.1074/jbc.M202684200. Epub 2002 Mar 29. J Biol Chem. 2002. PMID: 11925450 Free article.
245 results