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Targeting host cell furin proprotein convertases as a therapeutic strategy against bacterial toxins and viral pathogens.
Shiryaev SA, Remacle AG, Ratnikov BI, Nelson NA, Savinov AY, Wei G, Bottini M, Rega MF, Parent A, Desjardins R, Fugere M, Day R, Sabet M, Pellecchia M, Liddington RC, Smith JW, Mustelin T, Guiney DG, Lebl M, Strongin AY. Shiryaev SA, et al. Among authors: remacle ag. J Biol Chem. 2007 Jul 20;282(29):20847-53. doi: 10.1074/jbc.M703847200. Epub 2007 May 30. J Biol Chem. 2007. PMID: 17537721 Free article.
Inflammatory proprotein convertase-matrix metalloproteinase proteolytic pathway in antigen-presenting cells as a step to autoimmune multiple sclerosis.
Shiryaev SA, Remacle AG, Savinov AY, Chernov AV, Cieplak P, Radichev IA, Williams R, Shiryaeva TN, Gawlik K, Postnova TI, Ratnikov BI, Eroshkin AM, Motamedchaboki K, Smith JW, Strongin AY. Shiryaev SA, et al. Among authors: remacle ag. J Biol Chem. 2009 Oct 30;284(44):30615-26. doi: 10.1074/jbc.M109.041244. Epub 2009 Sep 2. J Biol Chem. 2009. PMID: 19726693 Free PMC article.
Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism.
D'Alessio S, Ferrari G, Cinnante K, Scheerer W, Galloway AC, Roses DF, Rozanov DV, Remacle AG, Oh ES, Shiryaev SA, Strongin AY, Pintucci G, Mignatti P. D'Alessio S, et al. Among authors: remacle ag. J Biol Chem. 2008 Jan 4;283(1):87-99. doi: 10.1074/jbc.M705492200. Epub 2007 Nov 8. J Biol Chem. 2008. PMID: 17991754 Free article.
54 results