Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

12 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain.
Ramírez-García PD, Retamal JS, Shenoy P, Imlach W, Sykes M, Truong N, Constandil L, Pelissier T, Nowell CJ, Khor SY, Layani LM, Lumb C, Poole DP, Lieu T, Stewart GD, Mai QN, Jensen DD, Latorre R, Scheff NN, Schmidt BL, Quinn JF, Whittaker MR, Veldhuis NA, Davis TP, Bunnett NW. Ramírez-García PD, et al. Among authors: retamal js. Nat Nanotechnol. 2019 Dec;14(12):1150-1159. doi: 10.1038/s41565-019-0568-x. Epub 2019 Nov 4. Nat Nanotechnol. 2019. PMID: 31686009 Free PMC article.
The transient receptor potential vanilloid 4 (TRPV4) ion channel mediates protease activated receptor 1 (PAR1)-induced vascular hyperpermeability.
Peng S, Grace MS, Gondin AB, Retamal JS, Dill L, Darby W, Bunnett NW, Abogadie FC, Carbone SE, Tigani T, Davis TP, Poole DP, Veldhuis NA, McIntyre P. Peng S, et al. Among authors: retamal js. Lab Invest. 2020 Aug;100(8):1057-1067. doi: 10.1038/s41374-020-0430-7. Epub 2020 Apr 27. Lab Invest. 2020. PMID: 32341518 Free PMC article.
A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes.
Mai QN, Shenoy P, Quach T, Retamal JS, Gondin AB, Yeatman HR, Aurelio L, Conner JW, Poole DP, Canals M, Nowell CJ, Graham B, Davis TP, Briddon SJ, Hill SJ, Porter CJH, Bunnett NW, Halls ML, Veldhuis NA. Mai QN, et al. Among authors: retamal js. J Biol Chem. 2021 Jan-Jun;296:100345. doi: 10.1016/j.jbc.2021.100345. Epub 2021 Jan 28. J Biol Chem. 2021. PMID: 33515548 Free PMC article.
Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of mice.
Retamal JS, Grace MS, Dill LK, Ramirez-Garcia P, Peng S, Gondin AB, Bennetts F, Alvi S, Rajasekhar P, Almazi JG, Carbone SE, Bunnett NW, Davis TP, Veldhuis NA, Poole DP, McIntyre P. Retamal JS, et al. Lab Invest. 2021 Jul;101(7):851-864. doi: 10.1038/s41374-021-00593-7. Epub 2021 Apr 15. Lab Invest. 2021. PMID: 33859334 Free PMC article.
Mice expressing fluorescent PAR2 reveal that endocytosis mediates colonic inflammation and pain.
Latorre R, Hegron A, Peach CJ, Teng S, Tonello R, Retamal JS, Klein-Cloud R, Bok D, Jensen DD, Gottesman-Katz L, Rientjes J, Veldhuis NA, Poole DP, Schmidt BL, Pothoulakis CH, Rankin C, Xie Y, Koon HW, Bunnett NW. Latorre R, et al. Among authors: retamal js. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2112059119. doi: 10.1073/pnas.2112059119. Proc Natl Acad Sci U S A. 2022. PMID: 35110404 Free PMC article.
Schwann cell endosome CGRP signals elicit periorbital mechanical allodynia in mice.
De Logu F, Nassini R, Hegron A, Landini L, Jensen DD, Latorre R, Ding J, Marini M, Souza Monteiro de Araujo D, Ramírez-Garcia P, Whittaker M, Retamal J, Titiz M, Innocenti A, Davis TP, Veldhuis N, Schmidt BL, Bunnett NW, Geppetti P. De Logu F, et al. Nat Commun. 2022 Feb 3;13(1):646. doi: 10.1038/s41467-022-28204-z. Nat Commun. 2022. PMID: 35115501 Free PMC article.
Sustained endosomal release of a neurokinin-1 receptor antagonist from nanostars provides long-lasting relief of chronic pain.
Latorre R, Ramírez-Garcia PD, Hegron A, Grace JL, Retamal JS, Shenoy P, Tran M, Aurelio L, Flynn B, Poole DP, Klein-Cloud R, Jensen DD, Davis TP, Schmidt BL, Quinn JF, Whittaker MR, Veldhuis NA, Bunnett NW. Latorre R, et al. Among authors: retamal js. Biomaterials. 2022 Jun;285:121536. doi: 10.1016/j.biomaterials.2022.121536. Epub 2022 Apr 28. Biomaterials. 2022. PMID: 35533442 Free PMC article.
12 results