Rettie AE - Search Results

1

Cytochrome P450 ω-Hydroxylases in Inflammation and Cancer.

Johnson AL, Edson KZ, Totah RA, Rettie AE. Johnson AL, et al. Among authors: rettie ae. Adv Pharmacol. 2015;74:223-62. doi: 10.1016/bs.apha.2015.05.002. Epub 2015 Jun 27. Adv Pharmacol. 2015. PMID: 26233909 Free PMC article. Review.

2

Identification of a meander region proline residue critical for heme binding to cytochrome P450: implications for the catalytic function of human CYP4B1.

Zheng YM, Fisher MB, Yokotani N, Fujii-Kuriyama Y, Rettie AE. Zheng YM, et al. Among authors: rettie ae. Biochemistry. 1998 Sep 15;37(37):12847-51. doi: 10.1021/bi981280m. Biochemistry. 1998. PMID: 9737862

3

Genotyping and site-directed mutagenesis of a cytochrome P450 meander Pro-X-Arg motif critical to CYP4B1 catalysis.

Zheng YM, Henne KR, Charmley P, Kim RB, McCarver DG, Cabacungan ET, Hines RN, Rettie AE. Zheng YM, et al. Among authors: rettie ae. Toxicol Appl Pharmacol. 2003 Jan 15;186(2):119-26. doi: 10.1016/s0041-008x(02)00028-5. Toxicol Appl Pharmacol. 2003. PMID: 12639503

4

Cytochrome P450 2C8: substrates, inhibitors, pharmacogenetics, and clinical relevance.

Totah RA, Rettie AE. Totah RA, et al. Among authors: rettie ae. Clin Pharmacol Ther. 2005 May;77(5):341-52. doi: 10.1016/j.clpt.2004.12.267. Clin Pharmacol Ther. 2005. PMID: 15900280 Review.

5

CYP4V2 in Bietti's crystalline dystrophy: ocular localization, metabolism of ω-3-polyunsaturated fatty acids, and functional deficit of the p.H331P variant.

Nakano M, Kelly EJ, Wiek C, Hanenberg H, Rettie AE. Nakano M, et al. Among authors: rettie ae. Mol Pharmacol. 2012 Oct;82(4):679-86. doi: 10.1124/mol.112.080085. Epub 2012 Jul 6. Mol Pharmacol. 2012. PMID: 22772592 Free PMC article.

6

ω-Hydroxylation of phylloquinone by CYP4F2 is not increased by α-tocopherol.

Farley SM, Leonard SW, Taylor AW, Birringer M, Edson KZ, Rettie AE, Traber MG. Farley SM, et al. Among authors: rettie ae. Mol Nutr Food Res. 2013 Oct;57(10):1785-93. doi: 10.1002/mnfr.201200797. Epub 2013 May 3. Mol Nutr Food Res. 2013. PMID: 23650179 Free PMC article.

7

CYP4 enzymes as potential drug targets: focus on enzyme multiplicity, inducers and inhibitors, and therapeutic modulation of 20-hydroxyeicosatetraenoic acid (20-HETE) synthase and fatty acid ω-hydroxylase activities.

Edson KZ, Rettie AE. Edson KZ, et al. Among authors: rettie ae. Curr Top Med Chem. 2013;13(12):1429-40. doi: 10.2174/15680266113139990110. Curr Top Med Chem. 2013. PMID: 23688133 Free PMC article. Review.

8

Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11.

Edson KZ, Prasad B, Unadkat JD, Suhara Y, Okano T, Guengerich FP, Rettie AE. Edson KZ, et al. Among authors: rettie ae. Biochemistry. 2013 Nov 19;52(46):8276-85. doi: 10.1021/bi401208m. Epub 2013 Nov 7. Biochemistry. 2013. PMID: 24138531 Free PMC article.

9

Ocular cytochrome P450s and transporters: roles in disease and endobiotic and xenobiotic disposition.

Nakano M, Lockhart CM, Kelly EJ, Rettie AE. Nakano M, et al. Among authors: rettie ae. Drug Metab Rev. 2014 Aug;46(3):247-60. doi: 10.3109/03602532.2014.921190. Epub 2014 May 26. Drug Metab Rev. 2014. PMID: 24856391 Free PMC article. Review.

10

Optimized human CYP4B1 in combination with the alkylator prodrug 4-ipomeanol serves as a novel suicide gene system for adoptive T-cell therapies.

Roellecke K, Virts EL, Einholz R, Edson KZ, Altvater B, Rossig C, von Laer D, Scheckenbach K, Wagenmann M, Reinhardt D, Kramm CM, Rettie AE, Wiek C, Hanenberg H. Roellecke K, et al. Among authors: rettie ae. Gene Ther. 2016 Jul;23(7):615-26. doi: 10.1038/gt.2016.38. Epub 2016 May 19. Gene Ther. 2016. PMID: 27092941

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