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RNA Helicase DDX24 Stabilizes LAMB1 to Promote Hepatocellular Carcinoma Progression.
Liu T, Gan H, He S, Deng J, Hu X, Li L, Cai L, He J, Long H, Cai J, Li H, Zhang Q, Wang L, Chen F, Chen Y, Zhang H, Li J, Yang L, Liu Y, Yang JH, Kuang DM, Pang P, He H, Shan H. Liu T, et al. Cancer Res. 2022 Sep 2;82(17):3074-3087. doi: 10.1158/0008-5472.CAN-21-3748. Cancer Res. 2022. PMID: 35763670
Mechanistically, DDX24 bound the mRNA618-624nt of laminin subunit beta 1 (LAMB1) and increased its stability in a manner dependent upon the interaction between nucleolin and the C-terminal region of DDX24. Moreover, regulatory factor X8 (RFX8) was identified as a DDX24 pro …
Mechanistically, DDX24 bound the mRNA618-624nt of laminin subunit beta 1 (LAMB1) and increased its stability in a manner dependent upon the …
Effect of Dietetic Obesity on Testicular Transcriptome in Cynomolgus Monkeys.
Zhang Y, Qi J, Zhao J, Li M, Zhang Y, Hu H, Wei L, Zhou K, Qin H, Qu P, Cao W, Liu E. Zhang Y, et al. Genes (Basel). 2023 Feb 23;14(3):557. doi: 10.3390/genes14030557. Genes (Basel). 2023. PMID: 36980830 Free PMC article.
We also found abnormal expression of genes related to infertility (TDRD5, CLCN2, MORC1, RFX8, SOHLH1, IL2RB, MCIDAS, ZPBP, NFIA, PTPN11, TSC22D3, MAPK6, PLCB1, DCUN1D1, LPIN1, and GATM) and down-regulation of testosterone in monkeys with dietetic obesity. ...
We also found abnormal expression of genes related to infertility (TDRD5, CLCN2, MORC1, RFX8, SOHLH1, IL2RB, MCIDAS, ZPBP, NFIA, PTPN …
Genome-Wide Association Studies Reveal Neurological Genes for Dog Herding, Predation, Temperament, and Trainability Traits.
Shan S, Xu F, Brenig B. Shan S, et al. Front Vet Sci. 2021 Jul 21;8:693290. doi: 10.3389/fvets.2021.693290. eCollection 2021. Front Vet Sci. 2021. PMID: 34368281 Free PMC article.
Significantly associated sites on CFA7, 9, 10, and 20 were located either in or near neuropathological or neuronal genes including THOC1, ASIC2, MSRB3, LLPH, RFX8, and CHL1. MSRB3 and CHL1 genes were reported to be associated with dog fear. ...Since dog behaviors are corre …
Significantly associated sites on CFA7, 9, 10, and 20 were located either in or near neuropathological or neuronal genes including THOC1, AS …
Characterization of the human RFX transcription factor family by regulatory and target gene analysis.
Sugiaman-Trapman D, Vitezic M, Jouhilahti EM, Mathelier A, Lauter G, Misra S, Daub CO, Kere J, Swoboda P. Sugiaman-Trapman D, et al. BMC Genomics. 2018 Mar 6;19(1):181. doi: 10.1186/s12864-018-4564-6. BMC Genomics. 2018. PMID: 29510665 Free PMC article.
We experimentally confirmed novel TSS locations and characterized the previously undescribed RFX8 to be lowly expressed. RFX tissue and cell type specificity arises mainly from differences in TSS architecture. ...
We experimentally confirmed novel TSS locations and characterized the previously undescribed RFX8 to be lowly expressed. RFX tissue a …
A genome-wide association study (GWAS) for pH value in the meat of Berkshire pigs.
Park J, Lee SM, Park JY, Na CS. Park J, et al. J Anim Sci Technol. 2021 Jan;63(1):25-35. doi: 10.5187/jast.2021.e17. Epub 2021 Jan 31. J Anim Sci Technol. 2021. PMID: 33987581 Free PMC article.
SNPs with an absolute value more than 4 standard deviations from the mean were selected as threshold markers, among the selected SNPs, protein-coding genes of pH45m and pH24h were detected in 6 and 4 SNPs, respectively. The distribution of coding genes <RFX8, CREG2, TBC …
SNPs with an absolute value more than 4 standard deviations from the mean were selected as threshold markers, among the selected SNPs, prote …
Identification of RFX5 as prognostic biomarker and associated with immune infiltration in stomach adenocarcinoma.
Guo L, Liu D. Guo L, et al. Eur J Med Res. 2022 Aug 31;27(1):164. doi: 10.1186/s40001-022-00794-w. Eur J Med Res. 2022. PMID: 36045400 Free PMC article.
METHODS: Online bioinformatics tools such as GSCALite, Kaplan-Meier Plotter, TIMER, LinkedOmics were used to explore the immunomodulatory function and clinical value of RFXs in STAD. RESULTS: The mRNA level of RFX1, RFX3, RFX4, RFX5, RFX7 and RFX8 was significantly elevate …
METHODS: Online bioinformatics tools such as GSCALite, Kaplan-Meier Plotter, TIMER, LinkedOmics were used to explore the immunomodulatory fu …
Prognostic Model of Eleven Genes Based on the Immune Microenvironment in Patients With Thymoma.
Yang Y, Xie L, Li C, Liu L, Ye X, Han J. Yang Y, et al. Front Genet. 2022 Feb 11;13:668696. doi: 10.3389/fgene.2022.668696. eCollection 2022. Front Genet. 2022. PMID: 35222524 Free PMC article.
An 11-genes signature prognostic model (CELF5, ODZ1, CD1C, DRP2, PTCRA, TSHR, HKDC1, KCTD19, RFX8, UGT3A2, and PRKCG) was constructed from 177 survival-related DEGs. ...
An 11-genes signature prognostic model (CELF5, ODZ1, CD1C, DRP2, PTCRA, TSHR, HKDC1, KCTD19, RFX8, UGT3A2, and PRKCG) was constructed …
Identification of candidate genes affecting the tibia quality in Nonghua duck.
Lu Y, Wei B, Yang Q, Han X, He X, Tao Q, Jiang S, Xu M, Bai Y, Zhang T, Bai L, Hu J, Liu H, Li L. Lu Y, et al. Poult Sci. 2024 Apr;103(4):103515. doi: 10.1016/j.psj.2024.103515. Epub 2024 Feb 1. Poult Sci. 2024. PMID: 38350390 Free PMC article.
Among the 11 candidate genes that were annotated, TAPT1, BST1, and STIM2 were related to the diameter indicator, ZNF652, IGF2BP1, CASK, and GREB1L were associated with the weight and toughness indicators. RFX8, GLP1R, and DNAAF5 were identified for ash, calcium, and phosph …
Among the 11 candidate genes that were annotated, TAPT1, BST1, and STIM2 were related to the diameter indicator, ZNF652, IGF2BP1, CASK, and …