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The scaffold RhoGAP protein ARHGAP8/BPGAP1 synchronizes Rac and Rho signaling to facilitate cell migration.
Wong DCP, Pan CQ, Er SY, Thivakar T, Rachel TZY, Seah SH, Chua PJ, Jiang T, Chew TW, Chaudhuri PK, Mukherjee S, Salim A, Aye TA, Koh CG, Lim CT, Tan PH, Bay BH, Ridley AJ, Low BC. Wong DCP, et al. Among authors: ridley aj. Mol Biol Cell. 2023 Mar 1;34(3):ar13. doi: 10.1091/mbc.E21-03-0099. Epub 2023 Jan 4. Mol Biol Cell. 2023. PMID: 36598812 Free PMC article.
Statins change the cytokine profile in Trypanosoma cruzi-infected U937 macrophages and murine cardiac tissue through Rho-associated kinases inhibition.
González-Herrera F, Clayton NS, Guzmán-Rivera D, Carrillo I, Castillo C, Catalán M, Anfossi R, Quintero-Pertuz H, Quilaqueo ME, Olea-Azar C, Rivera-Meza M, Kemmerling U, Ridley AJ, Vivar R, Maya JD. González-Herrera F, et al. Among authors: ridley aj. Front Immunol. 2023 Jan 11;13:1035589. doi: 10.3389/fimmu.2022.1035589. eCollection 2022. Front Immunol. 2023. PMID: 36713380 Free PMC article.
RhoU forms homo-oligomers to regulate cellular responses.
Clayton NS, Hodge RG, Infante E, Alibhai D, Zhou F, Ridley AJ. Clayton NS, et al. Among authors: ridley aj. J Cell Sci. 2024 Jan 15;137(2):jcs261645. doi: 10.1242/jcs.261645. Epub 2024 Jan 30. J Cell Sci. 2024. PMID: 38180080 Free PMC article.
Pulmonary inflammation promoted by type-2 dendritic cells is a feature of human and murine schistosomiasis.
Houlder EL, Costain AH, Nambuya I, Brown SL, Koopman JPR, Langenberg MCC, Janse JJ, Hoogerwerf MA, Ridley AJL, Forde-Thomas JE, Colombo SAP, Winkel BMF, Galdon AA, Hoffmann KF, Cook PC, Roestenberg M, Mpairwe H, MacDonald AS. Houlder EL, et al. Among authors: ridley ajl. Nat Commun. 2023 Apr 3;14(1):1863. doi: 10.1038/s41467-023-37502-z. Nat Commun. 2023. PMID: 37012228 Free PMC article.
Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors.
Gray AL, Karlsson R, Roberts ARE, Ridley AJL, Pun N, Khan B, Lawless C, Luís R, Szpakowska M, Chevigné A, Hughes CE, Medina-Ruiz L, Birchenough HL, Mulholland IZ, Salanga CL, Yates EA, Turnbull JE, Handel TM, Graham GJ, Jowitt TA, Schiessl I, Richter RP, Miller RL, Dyer DP. Gray AL, et al. Among authors: ridley ajl. Cell Rep. 2023 Jan 31;42(1):111930. doi: 10.1016/j.celrep.2022.111930. Epub 2023 Jan 5. Cell Rep. 2023. PMID: 36640356 Free PMC article.
228 results