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Phase 2, Dose-Ranging Study of Relebactam with Imipenem-Cilastatin in Subjects with Complicated Intra-abdominal Infection.
Lucasti C, Vasile L, Sandesc D, Venskutonis D, McLeroth P, Lala M, Rizk ML, Brown ML, Losada MC, Pedley A, Kartsonis NA, Paschke A. Lucasti C, et al. Among authors: rizk ml. Antimicrob Agents Chemother. 2016 Sep 23;60(10):6234-43. doi: 10.1128/AAC.00633-16. Print 2016 Oct. Antimicrob Agents Chemother. 2016. PMID: 27503659 Free PMC article. Clinical Trial.
Importance of Drug Pharmacokinetics at the Site of Action.
Rizk ML, Zou L, Savic RM, Dooley KE. Rizk ML, et al. Clin Transl Sci. 2017 May;10(3):133-142. doi: 10.1111/cts.12448. Epub 2017 Feb 3. Clin Transl Sci. 2017. PMID: 28160433 Free PMC article. Review. No abstract available.
Exploring the Pharmacokinetic/Pharmacodynamic Relationship of Relebactam (MK-7655) in Combination with Imipenem in a Hollow-Fiber Infection Model.
Wu J, Racine F, Wismer MK, Young K, Carr DM, Xiao JC, Katwaru R, Si Q, Harradine P, Motyl M, Bhagunde PR, Rizk ML. Wu J, et al. Among authors: rizk ml. Antimicrob Agents Chemother. 2018 Apr 26;62(5):e02323-17. doi: 10.1128/AAC.02323-17. Print 2018 May. Antimicrob Agents Chemother. 2018. PMID: 29507068 Free PMC article.
Pharmacokinetics, Safety, and Tolerability of Single and Multiple Doses of Relebactam, a β-Lactamase Inhibitor, in Combination with Imipenem and Cilastatin in Healthy Participants.
Rhee EG, Rizk ML, Calder N, Nefliu M, Warrington SJ, Schwartz MS, Mangin E, Boundy K, Bhagunde P, Colon-Gonzalez F, Jumes P, Liu Y, Butterton JR. Rhee EG, et al. Among authors: rizk ml. Antimicrob Agents Chemother. 2018 Aug 27;62(9):e00280-18. doi: 10.1128/AAC.00280-18. Print 2018 Sep. Antimicrob Agents Chemother. 2018. PMID: 29914955 Free PMC article.
52 results